WormBase Tree Display for Gene: HGNC:804
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| HGNC:804 | Identity | Name | CGC_name | Atp1b1 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name (13) | ||||||
| Public_name | Atp1b1 | |||||
| DB_info | Database | HGNC | id | 804 | ||
| AGR | cURI | HGNC:804 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000143153 | ||||
| UniProt | UniProt_AC | P05026 | ||||
| OMIM | gene | 182330 | ||||
| DO | id | DOID:10825 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00008074 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| OrthoFinder | ||||||
| Panther | ||||||
| WBGene00010117 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| WBGene00007646 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010] | Inferred_automatically | AGR_import |
