WormBase Tree Display for Gene: HGNC:6631
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| HGNC:6631 | Identity | Name | CGC_name | Lman1 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name (14) | ||||||
| Public_name | Lman1 | |||||
| DB_info | Database | HGNC | id | 6631 | ||
| AGR | cURI | HGNC:6631 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000074695 | ||||
| UniProt | UniProt_AC | P49257 | ||||
| DO | id | DOID:2211 | ||||
| DOID:2216 | ||||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00002070 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| Inparanoid | ||||||
| OMA | ||||||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| PhylomeDB | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015] | Inferred_automatically | AGR_import |
