WormBase Tree Display for Gene: HGNC:4617
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HGNC:4617 | Identity | Name | CGC_name | Gsk3b | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name | RGD:733891 | |||||
GSK-3 beta | ||||||
GSK3beta isoform | ||||||
glycogen synthase kinase-3 beta | ||||||
serine/threonine-protein kinase GSK3B | ||||||
Public_name | Gsk3b | |||||
DB_info | Database | HGNC | id | 4617 | ||
AGR | cURI | HGNC:4617 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000082701 | ||||
UniProt | UniProt_AC | P49841 | ||||
DO | id | DOID:10652 | ||||
DOID:0050866 | ||||||
DOID:3312 | ||||||
DOID:2871 | ||||||
DOID:0050861 | ||||||
DOID:332 | ||||||
DOID:90 | ||||||
DOID:5419 | ||||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00001746 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
Hieranoid | ||||||
Inparanoid | ||||||
OMA | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017] | Inferred_automatically | AGR_import |