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WormBase Tree Display for Gene: HGNC:4617

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Name Class

HGNC:4617IdentityNameCGC_nameGsk3bInferred_automaticallyAGR_import
Other_nameRGD:733891
GSK-3 beta
GSK3beta isoform
glycogen synthase kinase-3 beta
serine/threonine-protein kinase GSK3B
Public_nameGsk3b
DB_infoDatabaseHGNCid4617
AGRcURIHGNC:4617
EnsEMBLENSEMBL_geneIDENSG00000082701
UniProtUniProt_ACP49841
DOidDOID:10652
DOID:0050866
DOID:3312
DOID:2871
DOID:0050861
DOID:332
DOID:90
DOID:5419
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00001746Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThe protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]Inferred_automaticallyAGR_import