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WormBase Tree Display for Gene: HGNC:11250

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Name Class

HGNC:11250IdentityNameCGC_nameSpo11Inferred_automaticallyAGR_import
Other_name (16)
Public_nameSpo11
DB_infoDatabaseHGNCid11250
AGRcURIHGNC:11250
EnsEMBLENSEMBL_geneIDENSG00000054796
UniProtUniProt_ACQ9Y5K1
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00004985Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionMeiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import