WormBase Tree Display for Gene: HGNC:1074
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| HGNC:1074 | Identity | Name | CGC_name | Bmp7 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:1344234 | |||||
| BMP-7 | ||||||
| OP-1 | ||||||
| osteogenic protein 1 | ||||||
| Public_name | Bmp7 | |||||
| DB_info | Database | HGNC | id | 1074 | ||
| AGR | cURI | HGNC:1074 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000101144 | ||||
| UniProt | UniProt_AC | P18075 | ||||
| DO | id | DOID:4450 | ||||
| DOID:10283 | ||||||
| DOID:4001 | ||||||
| DOID:1612 | ||||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006570 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| OrthoFinder | ||||||
| PhylomeDB | ||||||
| WBGene00000936 | Caenorhabditis elegans | From_analysis | Hieranoid | |||
| Inparanoid | ||||||
| OrthoInspector | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016] | Inferred_automatically | AGR_import |
