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WormBase Tree Display for Gene: HGNC:10659

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Name Class

HGNC:10659IdentityNameCGC_nameSdc2Inferred_automaticallyAGR_import
Other_name (11)
Public_nameSdc2
DB_infoDatabaseHGNCid10659
AGRcURIHGNC:10659
EnsEMBLENSEMBL_geneIDENSG00000169439
UniProtUniProt_ACP34741
DOidDOID:9296
DOID:9352
DOID:674
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00004749Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
Panther
SonicParanoid
Structured_descriptionAutomated_descriptionThe protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import