WormBase Tree Display for Gene: HGNC:10659
expand all nodes | collapse all nodes | view schema
HGNC:10659 | Identity | Name | CGC_name | Sdc2 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Other_name (11) | ||||||
Public_name | Sdc2 | |||||
DB_info | Database | HGNC | id | 10659 | ||
AGR | cURI | HGNC:10659 | ||||
EnsEMBL | ENSEMBL_geneID | ENSG00000169439 | ||||
UniProt | UniProt_AC | P34741 | ||||
DO | id | DOID:9296 | ||||
DOID:9352 | ||||||
DOID:674 | ||||||
Species | Homo sapiens | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00004749 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
Inparanoid | ||||||
OrthoFinder | ||||||
Panther | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |