WormBase Tree Display for Gene: FB:FBgn0026598
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| FB:FBgn0026598 | Identity | Name | CGC_name | Apc2 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | FB:CG6193 | |||||
| Public_name | Apc2 | |||||
| DB_info | Database | FLYBASE | id | FBgn0026598 | ||
| AGR | cURI | FB:FBgn0026598 | ||||
| UniProt | UniProt_AC | Q9Y1T2 | ||||
| A0A1Z1CN92 | ||||||
| Q961B0 | ||||||
| Species | Drosophila melanogaster | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00000156 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| OrthoFinder | ||||||
| OrthoInspector | ||||||
| Panther | ||||||
| SonicParanoid | ||||||
| Structured_description | Automated_description | Adenomatous polyposis coli 2 (Apc2) encodes one of two Drosophila APC family proteins. It is a key negative regulator of Wingless signaling, as a critical component of the destruction complex that phosphorylates beta-catenin and thus targets it for ubiquitination and proteasomal destruction. It is the primary APC family member during embryonic development, and functions redundantly with the product of Apc in adult development. | Inferred_automatically | AGR_import |
