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WormBase Tree Display for Gene: WBGene00000457

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Name Class

WBGene00000457SMapS_parentSequenceC37E2
IdentityVersion1
NameCGC_nameceh-36Person_evidenceWBPerson83
Sequence_nameC37E2.4
Molecular_nameC37E2.4
C37E2.4.1
CE08623
Other_nameCELE_C37E2.4Accession_evidenceNDBBX284606
Public_nameceh-36
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classceh
Allele (73)
StrainWBStrain00006685
WBStrain00029360
WBStrain00029396
WBStrain00029397
WBStrain00029398
WBStrain00029399
WBStrain00029400
WBStrain00029428
WBStrain00029429
WBStrain00029430
WBStrain00029431
WBStrain00029432
WBStrain00029433
WBStrain00029434
WBStrain00029452
WBStrain00029461
WBStrain00029463
WBStrain00029464
WBStrain00029485
WBStrain00035889
WBStrain00005275
WBStrain00005276
WBStrain00007515
WBStrain00022465
WBStrain00049275
WBStrain00049307
WBStrain00050853
WBStrain00055073
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (23)
Paralog (20)
Structured_descriptionConcise_descriptionceh-36 encodes a paired-like homeodomain transcription factor that is one of three orthodenticle (OTX/OTD) homeodomain proteins in C. elegans (the others being TTX-1 and CEH-37); CEH-36 is required broadly for specification of the AWC olfactory neuron and also for establishing the left-right asymmetry of the ASEL and ASER gustatory neurons; in addition, CEH-36 is sufficient to specify the AFD thermosensory neuron fate in some cell types; CEH-36 is expressed in the AWC and ASE chemosensory neurons.Paper_evidenceWBPaper00006146
Curator_confirmedWBPerson1843
Date_last_updated03 Nov 2008 00:00:00
Automated_descriptionEnables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in neuron fate specification; positive regulation of transcription by RNA polymerase II; and sensory perception of chemical stimulus. Located in nucleus. Expressed in ABaraappa; ABaraappaa; amphid neurons; and head neurons. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 5. Is an ortholog of human ARGFX (arginine-fifty homeobox); DPRX (divergent-paired related homeobox); and NOBOX (NOBOX oogenesis homeobox).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080862Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:22448)
Molecular_infoCorresponding_CDSC37E2.4
Corresponding_transcriptC37E2.4.1
Other_sequenceAcan_isotig20892
CRC06706_1
Dviv_isotig18862
CR03746
Dviv_isotig18863
Associated_feature (13)
Gene_product_binds (3)
Transcription_factorWBTranscriptionFactor000158
Experimental_infoRNAi_resultWBRNAi00093990Inferred_automaticallyRNAi_primary
WBRNAi00001118Inferred_automaticallyRNAi_primary
WBRNAi00029642Inferred_automaticallyRNAi_primary
WBRNAi00011721Inferred_automaticallyRNAi_primary
WBRNAi00042116Inferred_automaticallyRNAi_primary
Expr_pattern (23)
Drives_construct (46)
Construct_productWBCnstr00007677
WBCnstr00010927
WBCnstr00011003
WBCnstr00018896
WBCnstr00022542
WBCnstr00022977
WBCnstr00037522
Microarray_results (19)
Expression_cluster (115)
Interaction (126)
Anatomy_functionWBbtf0392
Map_infoMapXPosition16.6588Error0.001314
PositivePositive_cloneC37E2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4209
Pseudo_map_position
Reference (87)
Remark[Burglin T] registered gene name
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene