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WormBase Tree Display for Gene: WBGene00021043

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Name Class

WBGene00021043SMapS_parentSequenceW05G11
IdentityVersion2
NameCGC_namepck-1Person_evidenceWBPerson2192
Sequence_nameW05G11.6
Molecular_nameW05G11.6
W05G11.6.1
CE19610
Other_nameCELE_W05G11.6Accession_evidenceNDBBX284603
Public_namepck-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
217 Feb 2012 16:57:01WBPerson2970Name_changeCGC_namepck-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpck
Allele (218)
StrainWBStrain00032381
RNASeq_FPKM (74)
GO_annotation (24)
Ortholog (41)
ParalogWBGene00011232Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019151Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionpck-1 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of W05G11.6 are predicted to function in gluconeogenesis.Curator_confirmedWBPerson1843
Date_last_updated27 Jul 2012 00:00:00
Automated_descriptionPredicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Located in cytosol and striated muscle dense body. Expressed in several structures, including body wall musculature; preanal ganglion; somatic nervous system; tail ganglion; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8724)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8724)
Molecular_infoCorresponding_CDSW05G11.6
Corresponding_CDS_historyW05G11.6b:wp275
W05G11.6d:wp275
Corresponding_transcriptW05G11.6.1
Other_sequence (167)
Associated_feature (15)
Experimental_infoRNAi_result (13)
Expr_patternExpr9397
Expr15024
Expr15026
Expr1024494
Expr1039172
Expr1158379
Expr2014778
Expr2033012
Drives_construct (3)
Construct_productWBCnstr00013962
WBCnstr00041876
WBCnstr00042950
WBCnstr00042951
Microarray_results (39)
Expression_cluster (317)
Interaction (47)
Map_infoMapIIIPosition-27.1341
PositivePositive_cloneW05G11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026800
WBPaper00027145
WBPaper00029292
WBPaper00033086
WBPaper00038444
WBPaper00038491
WBPaper00041315
WBPaper00053236
WBPaper00055090
WBPaper00057505
WBPaper00058434
WBPaper00059520
WBPaper00060127
WBPaper00061616
WBPaper00062625
WBPaper00064602
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene