Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00010317

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00010317SMapS_parentSequenceF59B8
IdentityVersion2
NameCGC_nameidh-1Person_evidenceWBPerson261
Sequence_nameF59B8.2
Molecular_nameF59B8.2a
F59B8.2a.1
CE03436
F59B8.2b
CE47303
F59B8.2c
CE47163
F59B8.2b.1
F59B8.2c.1
Other_nameCELE_F59B8.2Accession_evidenceNDBBX284604
Public_nameidh-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
208 Oct 2008 10:23:18WBPerson2970Name_changeCGC_nameidh-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classidh
Allele (27)
StrainWBStrain00003527
WBStrain00002807
WBStrain00032810
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (38)
ParalogWBGene00007942Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionidh-1 encodes a predicted cytosolic isocitrate dehydrogenase; by homology, IDH-1 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate.Curator_confirmedWBPerson1843
Date_last_updated26 Oct 2011 00:00:00
Automated_descriptionPredicted to enable isocitrate dehydrogenase (NADP+) activity. Predicted to be involved in NADP metabolic process and isocitrate metabolic process. Predicted to be located in cytosol; mitochondrion; and peroxisome. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); glioblastoma; and hematologic cancer (multiple). Is an ortholog of human IDH1 (isocitrate dehydrogenase (NADP(+)) 1).Paper_evidenceWBPaper00065943
Curator_confirmed (2)
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:5016Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:4928Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3068Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:0050908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3910Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3070Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3907Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:417Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:9119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
Molecular_infoCorresponding_CDSF59B8.2a
F59B8.2b
F59B8.2c
Corresponding_transcriptF59B8.2a.1
F59B8.2b.1
F59B8.2c.1
Other_sequence (57)
Associated_featureWBsf668157
WBsf668158
WBsf981804
WBsf997420
WBsf1017963
WBsf230567
WBsf230568
WBsf230569
Experimental_infoRNAi_resultWBRNAi00090634Inferred_automaticallyRNAi_primary
WBRNAi00080812Inferred_automaticallyRNAi_primary
WBRNAi00065271Inferred_automaticallyRNAi_primary
WBRNAi00016084Inferred_automaticallyRNAi_primary
WBRNAi00001636Inferred_automaticallyRNAi_primary
WBRNAi00033293Inferred_automaticallyRNAi_primary
WBRNAi00049155Inferred_automaticallyRNAi_primary
WBRNAi00113980Inferred_automaticallyRNAi_primary
Expr_patternChronogram1063
Chronogram1718
Expr6263
Expr6264
Expr1018358
Expr1034502
Expr1152898
Expr2012669
Expr2030905
Drives_constructWBCnstr00003334
WBCnstr00004581
WBCnstr00031510
Construct_productWBCnstr00031510
Microarray_results (25)
Expression_cluster (219)
Interaction (103)
Map_infoMapIVPosition4.24582Error0.002337
PositivePositive_cloneF59B8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026952
WBPaper00027145
WBPaper00031648
WBPaper00033003
WBPaper00033162
WBPaper00037414
WBPaper00038491
WBPaper00044730
WBPaper00055090
WBPaper00056058
WBPaper00063380
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene