WormBase Tree Display for Gene: WBGene00006913
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WBGene00006913 | SMap | S_parent | Sequence | T01H3 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | vha-4 | |||||
Sequence_name | T01H3.1 | ||||||
Molecular_name | T01H3.1 | ||||||
T01H3.1.1 | |||||||
CE03595 | |||||||
Other_name | CELE_T01H3.1 | Accession_evidence | NDB | BX284602 | |||
Public_name | vha-4 | ||||||
DB_info | Database | AceView | gene | 2I168 | |||
WormQTL | gene | WBGene00006913 | |||||
WormFlux | gene | WBGene00006913 | |||||
NDB | locus_tag | CELE_T01H3.1 | |||||
Panther | gene | CAEEL|WormBase=WBGene00006913|UniProtKB=G5EDB8 | |||||
family | PTHR10263 | ||||||
NCBI | gene | 174272 | |||||
RefSeq | protein | NM_063258.9 | |||||
SwissProt | UniProtAcc | G5EDB8 | |||||
TREEFAM | TREEFAM_ID | TF314946 | |||||
UniProt_GCRP | UniProtAcc | G5EDB8 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Acquires_merge | WBGene00011347 | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | vha | ||||||
Allele (11) | |||||||
Legacy_information | [Oka T, Yamamoto R, Futai M] vha for Vacuolar-type H+ ATPase. Encodes 23kD proteolipid. vha-4::GFP strongly expressed in excretory cell, rectum and two post-anal cells. Predicted gene T01H3.1. | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00013678 | ||||||
00013679 | |||||||
00013680 | |||||||
00013681 | |||||||
00013682 | |||||||
00114995 | |||||||
00114996 | |||||||
00114997 | |||||||
Contained_in_operon | CEOP2316 | ||||||
Ortholog (41) | |||||||
Paralog | WBGene00006910 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00006911 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00006912 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | vha-4 encodes an ortholog of subunit c'' of the membrane-bound (V0)domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-4 is apredicted V-ATPase transmembrane rotor component; VHA-4 is paralogous tothe c subunits VHA-1/-2/-3, and is predicted to help carry protons fromthe cytosol to a-subunits (VHA-5, VHA-6, VHA-7, or UNC-32) fortransmembrane export; VHA-4 is required for ovulation and embryogenesis,since vha-4(RNAi) animals are sterile with polyploid, unmatured oocytesand dead progeny; VHA-4 is required for alae formation, like the V0subunits VHA-1 and VHA-5, but not like the V1 subunits VHA-8 or VHA-13;vha-4 is expressed in the excretory cell, the rectum, and a pair ofcells near the anus. | Paper_evidence | WBPaper00002899 | |||
WBPaper00004341 | |||||||
WBPaper00027697 | |||||||
WBPaper00028773 | |||||||
WBPaper00028774 | |||||||
WBPaper00028775 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson567 | |||||||
Date_last_updated | 19 Nov 2006 00:00:00 | ||||||
Automated_description | Predicted to enable proton transmembrane transporter activity. Involved in embryo development. Predicted to be located in membrane. Predicted to be part of proton-transporting two-sector ATPase complex, proton-transporting domain. Expressed in excretory cell and rectum. Is an ortholog of human ATP6V0B (ATPase H+ transporting V0 subunit b). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T01H3.1 | |||||
Corresponding_transcript | T01H3.1.1 | ||||||
Other_sequence (73) | |||||||
Associated_feature | WBsf650276 | ||||||
WBsf650277 | |||||||
WBsf665747 | |||||||
WBsf665748 | |||||||
WBsf988587 | |||||||
WBsf223415 | |||||||
Experimental_info | RNAi_result (20) | ||||||
Expr_pattern | Expr1400 | ||||||
Expr1462 | |||||||
Expr1016340 | |||||||
Expr1032930 | |||||||
Expr1155804 | |||||||
Expr2017990 | |||||||
Expr2036126 | |||||||
Drives_construct | WBCnstr00007708 | ||||||
WBCnstr00010291 | |||||||
WBCnstr00034102 | |||||||
Construct_product | WBCnstr00010291 | ||||||
WBCnstr00034102 | |||||||
Microarray_results (22) | |||||||
Expression_cluster (109) | |||||||
Interaction (49) | |||||||
Map_info | Map | II | Position | 0.595594 | Error | 0.001171 | |
Positive | Positive_clone | T01H3 | Person_evidence | WBPerson5079 | |||
WBPerson5074 | |||||||
Author_evidence | Yamamoto R | ||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
Pseudo_map_position | |||||||
Reference | WBPaper00002899 | ||||||
WBPaper00003195 | |||||||
WBPaper00004842 | |||||||
WBPaper00011821 | |||||||
WBPaper00011885 | |||||||
WBPaper00027697 | |||||||
WBPaper00032236 | |||||||
WBPaper00036659 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00058870 | |||||||
WBPaper00059755 | |||||||
WBPaper00062277 | |||||||
Remark | Data extracted from Oka et al. (1997) | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |