WormBase Tree Display for Gene: WBGene00006788

WBGene00006788 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 1
    Name: CGC_name: unc-53 Person_evidence: WBPerson261
      Sequence_name: F45E10.1
      Molecular_name (24)
      Other_name: CELE_F45E10.1 Accession_evidence: NDB BX284602
      Public_name: unc-53
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:42 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: unc
    Reference_allele: WBVar00143183
    Allele (424)
    Legacy_information: e404 : sluggish poor backing dumpyish somewhat Egl; males have abnormal bursal anatomy. ES2 ME0. NA4 (n152 n166 n569).
      See also e2432, e2499, n152, n166, n569
      [C.elegansII] e404 : sluggish, poor backing, dumpyish; somewhat Egl; multiple defects in neuronal outgrowth, branching; also defects in excretory canal extension, gonad arm growth; males have abnormal bursal anatomy. ES2 ME0. OA>5: n152, n166, n569 (synergizes with sem-5(n177) to give strong Sem migration defect),e2432, e2499, etc. Null phenotype uncertain; some lethality in strong alleles. Cloned: multiple transcripts (different 5' ends); one encodes 1528 aa protein, predicted to bind actin, ATP/GTP; may interact with SEM-5. Transgene overexpression leads to extension of growth cones along a-p axis. [Hedgecock et al. 1987; Hekimi and Kershaw 1993; UG]
    Strain: WBStrain00026706
      WBStrain00026870
      WBStrain00032757
      WBStrain00034470
      WBStrain00034483
      WBStrain00037045
      WBStrain00004162
      WBStrain00004572
      WBStrain00005655
    RNASeq_FPKM (74)
    GO_annotation (21)
    Ortholog (46)
    Structured_description (2)
  Disease_info: Potential_model: DOID:2559 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:15998)
  Molecular_info: Corresponding_CDS: F45E10.1a
      F45E10.1b
      F45E10.1c
      F45E10.1d
      F45E10.1e
      F45E10.1f
      F45E10.1g
      F45E10.1h
    Corresponding_CDS_history: F45E10.1:wp82
    Corresponding_transcript (8)
    Other_sequence (27)
    Associated_feature (66)
  Experimental_info: RNAi_result (14)
    Expr_pattern (12)
    Drives_construct (25)
    Construct_product: WBCnstr00009444
      WBCnstr00010519
      WBCnstr00010520
      WBCnstr00010521
      WBCnstr00034150
    Antibody: WBAntibody00001615
      WBAntibody00001625
    Microarray_results (40)
    Expression_cluster (219)
    Interaction (103)
    Anatomy_function: WBbtf0113
      WBbtf0114
      WBbtf0118
      WBbtf0119
  Map_info: Map: II Position: 3.16568 Error: 0.005694
    Well_ordered
    Positive: Positive_clone: F45E10 Inferred_automatically: From sequence, transcript, pseudogene data
        T28D2
    Mapping_data: 2_point: 43
      Multi_point (11)
      Pos_neg_data: 2145
        2146
        2159
        2163
        4533
        4534
        4535
        4536
        4539
        10562
  Reference: WBPaper00000031
    WBPaper00000608
    WBPaper00000635
    WBPaper00000978
    WBPaper00001255
    WBPaper00001296
    WBPaper00001310
    WBPaper00001345
    WBPaper00001668
    WBPaper00001685
    WBPaper00001722
    WBPaper00001814
    WBPaper00002001
    WBPaper00002003
    WBPaper00002655
    WBPaper00002774
    WBPaper00003165
    WBPaper00004362
    WBPaper00005236
    WBPaper00005353
    WBPaper00006104
    WBPaper00010591
    WBPaper00010928
    WBPaper00011047
    WBPaper00011124
    WBPaper00011580
    WBPaper00011608
    WBPaper00011826
    WBPaper00011833
    WBPaper00013027
    WBPaper00013084
    WBPaper00013087
    WBPaper00014130
    WBPaper00014166
    WBPaper00014523
    WBPaper00014541
    WBPaper00014592
    WBPaper00014898
    WBPaper00015612
    WBPaper00016603
    WBPaper00016604
    WBPaper00017232
    WBPaper00017709
    WBPaper00018375
    WBPaper00018431
    WBPaper00019262
    WBPaper00019269
    WBPaper00020938
    WBPaper00021076
    WBPaper00021085
    WBPaper00021964
    WBPaper00022043
    WBPaper00022132
    WBPaper00022306
    WBPaper00022520
    WBPaper00022617
    WBPaper00022806
    WBPaper00023096
    WBPaper00023211
    WBPaper00023530
    WBPaper00023548
    WBPaper00023550
    WBPaper00023579
    WBPaper00023751
    WBPaper00023752
    WBPaper00026813
    WBPaper00027119
    WBPaper00027192
    WBPaper00029020
    WBPaper00029075
    WBPaper00030276
    WBPaper00030279
    WBPaper00031865
    WBPaper00031872
    WBPaper00032134
    WBPaper00032446
    WBPaper00032452
    WBPaper00032514
    WBPaper00033533
    WBPaper00034045
    WBPaper00034348
    WBPaper00034622
    WBPaper00036886
    WBPaper00038491
    WBPaper00038663
    WBPaper00040235
    WBPaper00041596
    WBPaper00043295
    WBPaper00044388
    WBPaper00044635
    WBPaper00046126
    WBPaper00048262
    WBPaper00051452
    WBPaper00053282
    WBPaper00055090
    WBPaper00059400
    WBPaper00063042
    WBPaper00063704
    WBPaper00065022
  Method: Gene