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WormBase Tree Display for Gene: WBGene00004986

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Name Class

WBGene00004986SMapS_parentSequenceT07C4
IdentityVersion1
NameCGC_namespp-1
Sequence_nameT07C4.4
Molecular_nameT07C4.4
T07C4.4.1
CE35363
Other_nameCELE_T07C4.4Accession_evidenceNDBBX284603
Public_namespp-1
DB_infoDatabaseAceViewgene3L444
WormQTLgeneWBGene00004986
WormFluxgeneWBGene00004986
NDBlocus_tagCELE_T07C4.4
NCBIgene176452
RefSeqproteinNM_066889.8
TREEFAMTREEFAM_IDTF322432
TrEMBLUniProtAccQ22291
UniProt_GCRPUniProtAccQ22291
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:37WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classspp
AlleleWBVar01500260
WBVar01499545
WBVar00407186
WBVar01499774
WBVar02019092
WBVar00093807
WBVar00252252
WBVar00855993
StrainWBStrain00032729
RNASeq_FPKM (74)
GO_annotation (14)
Contained_in_operonCEOP3839
Ortholog (22)
ParalogWBGene00004997Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
WormBase-Compara
Structured_descriptionConcise_descriptionspp-1 encodes a caenopore, a saposin (B) domain-containing protein that is a member of the saposin-like protein (SAPLIP) superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapore-like proteins; SPP-1 exhibits antibacterial activity in vitro and its expression in vivo is regulated by the DAF-2/insulin receptor signaling pathway and by the presence of bacterial pathogens such as Salmonella typhimurium and Pseudomonas aeruginosa; an spp-1::gfp reporter fusion is expressed in the intestine.Paper_evidenceWBPaper00003435
WBPaper00005976
WBPaper00029438
WBPaper00031463
WBPaper00032276
WBPaper00035289
WBPaper00041035
Curator_confirmedWBPerson1843
Date_last_updated05 Jul 2012 00:00:00
Automated_descriptionEnables pore-forming activity. Involved in defense response to other organism and pore formation in membrane of another organism. Part of pore complex.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST07C4.4
Corresponding_CDS_historyT07C4.4:wp108
Corresponding_transcriptT07C4.4.1
Other_sequenceCR10745
CBC10698_1
CRC07559_1
Associated_featureWBsf227443
Experimental_infoRNAi_result (34)
Expr_patternExpr4718
Expr8002
Expr1020872
Expr1032482
Expr1156337
Expr2016075
Expr2034311
Drives_constructWBCnstr00012195
WBCnstr00035291
Construct_product (2)
Microarray_results (25)
Expression_cluster (247)
Interaction (20)
WBProcessWBbiopr:00000008
WBbiopr:00000039
Map_infoMapIIIPosition2.4671Error0.002388
PositivePositive_cloneT07C4Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00003435
WBPaper00005976
WBPaper00006437
WBPaper00024209
WBPaper00025088
WBPaper00025180
WBPaper00027295
WBPaper00028482
WBPaper00029438
WBPaper00031463
WBPaper00032276
WBPaper00032370
WBPaper00032570
WBPaper00033181
WBPaper00035289
WBPaper00036653
WBPaper00040853
WBPaper00041035
WBPaper00042367
WBPaper00044217
WBPaper00045930
WBPaper00048424
WBPaper00051227
WBPaper00051307
WBPaper00055320
WBPaper00059071
WBPaper00061774
WBPaper00062392
WBPaper00062444
WBPaper00064183
WBPaper00064781
WBPaper00064949
WBPaper00065331
WBPaper00065681
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene