WormBase Tree Display for Gene: WBGene00004270
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WBGene00004270 | SMap | S_parent | Sequence | T25G12 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rab | ||||||
Allele (29) | |||||||
Strain | WBStrain00001717 | ||||||
WBStrain00001718 | |||||||
WBStrain00037087 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (36) | |||||||
Ortholog (50) | |||||||
Paralog (32) | |||||||
Structured_description | Concise_description | rab-6.2 encodes a small, monomeric Rab GTPase that is most closely related to the Drosophila and mammalian Rab6 GTPases; by homology, RAB-6.2 is predicted to function in the regulation of intracellular membrane trafficking; RNAi experiments indicate that rab-6.2 is required redundantly with rab-6.1 for normal embryonic development and reproduction; a RAB-6.2::GFP fusion protein localizes to the Golgi cisternae; RAB-6.2 physically interacts with VPS-52, a GARP (Golgi associated retrograde protein) complex subunit, in vivo. | Paper_evidence | WBPaper00030808 | |||
WBPaper00038455 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 13 Jan 2012 00:00:00 | ||||||
Automated_description | Enables GTP binding activity. Involved in several processes, including early endosome to Golgi transport; positive regulation of feeding behavior; and protein stabilization. Located in Golgi trans cisterna. Expressed in several structures, including coelomocyte; command interneuron; gonad; pharynx; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family) and RAB6B (RAB6B, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T25G12.4 | |||||
Corresponding_transcript | T25G12.4.1 | ||||||
Other_sequence (50) | |||||||
Associated_feature | WBsf655243 | ||||||
WBsf1008841 | |||||||
WBsf1024977 | |||||||
WBsf236886 | |||||||
WBsf236887 | |||||||
WBsf236888 | |||||||
WBsf236889 | |||||||
WBsf236890 | |||||||
Experimental_info | RNAi_result (11) | ||||||
Expr_pattern (11) | |||||||
Drives_construct | WBCnstr00002541 | ||||||
WBCnstr00002542 | |||||||
WBCnstr00014399 | |||||||
WBCnstr00015514 | |||||||
WBCnstr00018181 | |||||||
WBCnstr00035597 | |||||||
Construct_product | WBCnstr00008290 | ||||||
WBCnstr00014399 | |||||||
WBCnstr00015121 | |||||||
WBCnstr00015514 | |||||||
WBCnstr00019185 | |||||||
WBCnstr00035597 | |||||||
Microarray_results (20) | |||||||
Expression_cluster (151) | |||||||
Interaction (108) | |||||||
Map_info | Map | X | Position | 24.0866 | Error | 0.000393 | |
Positive | Positive_clone | T25G12 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 5259 | |||||
4748 | |||||||
5589 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00024112 | ||||||
WBPaper00025137 | |||||||
WBPaper00027296 | |||||||
WBPaper00029101 | |||||||
WBPaper00030935 | |||||||
WBPaper00038455 | |||||||
WBPaper00038491 | |||||||
WBPaper00038622 | |||||||
WBPaper00040563 | |||||||
WBPaper00041559 | |||||||
WBPaper00042474 | |||||||
WBPaper00042868 | |||||||
WBPaper00044965 | |||||||
WBPaper00048950 | |||||||
WBPaper00049258 | |||||||
WBPaper00052059 | |||||||
WBPaper00055090 | |||||||
WBPaper00056075 | |||||||
WBPaper00056338 | |||||||
WBPaper00057838 | |||||||
WBPaper00058219 | |||||||
WBPaper00061289 | |||||||
WBPaper00064057 | |||||||
WBPaper00065357 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |