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WormBase Tree Display for Gene: WBGene00003851

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Name Class

WBGene00003851SMapS_parentSequenceY102E9
IdentityVersion1
NameCGC_nameodr-4Person_evidenceWBPerson42
Sequence_nameY102E9.1
Molecular_name (12)
Other_nameCELE_Y102E9.1Accession_evidenceNDBBX284603
Public_nameodr-4
DB_infoDatabaseAceViewgene3H823
WormQTLgeneWBGene00003851
WormFluxgeneWBGene00003851
NDBlocus_tagCELE_Y102E9.1
PanthergeneCAEEL|WormBase=WBGene00003851|UniProtKB=Q8I7F8
familyPTHR33966
NCBIgene175950
RefSeqproteinNM_001027644.9
NM_001382900.2
NM_001392129.1
SwissProtUniProtAccQ8I7F8
TREEFAMTREEFAM_IDTF320359
UniProt_GCRPUniProtAccQ8I7F8
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classodr
Allele (48)
Legacy_information[Bargmann CI] defective chemotaxis to volatile odorants
[C.elegansII] n2144 : defective chemotaxis to some volatile odoratants. n2144/Df similar. NA1. [Bargmann et al. 1993]
[Dwyer ND] n2144 defective in odorant response to benzaldehyde, diacetyl, normal response to isoamyl alcohol, pyrazine. Fails to localize ODR-10 to cilia of AWA neurons. n2144 rescued by subclone including Y102E9.1, encoding 445 aa protein. n2144 is M372L plus splice acceptor change.
StrainWBStrain00027204
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (31)
Structured_descriptionConcise_descriptionodr-4 encodes a novel type II membrane protein; ODR-4 is required for localization of a subset of G protein-coupled receptors (GPCRs)s, including ODR-10, to the cilia of olfactory neurons; ODR-4 affects response to a subset of AWA- and AWC- mediated olfactory responses, and is required for social feeding of npr-1 mutant animals; ODR-4 physically interacts with ODR-8 to form a complex at the endoplasmic reticulum membrane, and physically interacts wtih ODR-10, as well; ODR-4 is expressed in twelve pairs of chemosensory neurons: the ten amphid neurons and two phasmid neurons; odr-4 expression overlaps that of odr-8.Paper_evidenceWBPaper00003063
WBPaper00005511
WBPaper00044965
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated02 May 2014 00:00:00
Automated_descriptionInvolved in olfactory behavior; receptor localization to non-motile cilium; and response to odorant. Located in intracellular membrane-bounded organelle and protein-containing complex. Expressed in chemosensory neurons and neurons. Is an ortholog of human ODR4 (odr-4 GPCR localization factor homolog).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY102E9.1a
Y102E9.1b
Y102E9.1c
Corresponding_transcriptY102E9.1a.1
Y102E9.1a.2
Y102E9.1a.3
Y102E9.1a.4
Y102E9.1b.1
Y102E9.1c.1
Other_sequence (31)
Associated_feature (6)
Experimental_infoRNAi_resultWBRNAi00005178Inferred_automaticallyRNAi_primary
WBRNAi00055160Inferred_automaticallyRNAi_primary
WBRNAi00005789Inferred_automaticallyRNAi_primary
WBRNAi00055159Inferred_automaticallyRNAi_primary
WBRNAi00005790Inferred_automaticallyRNAi_primary
WBRNAi00055161Inferred_automaticallyRNAi_primary
WBRNAi00055157Inferred_automaticallyRNAi_primary
WBRNAi00019822Inferred_automaticallyRNAi_primary
WBRNAi00005720Inferred_automaticallyRNAi_primary
WBRNAi00027800Inferred_automaticallyRNAi_primary
Expr_patternExpr1432
Expr10139
Expr11650
Expr13173
Expr1011843
Expr1031817
Expr1158687
Expr2014610
Expr2032843
Drives_constructWBCnstr00010274
WBCnstr00019303
WBCnstr00021696
WBCnstr00035829
WBCnstr00041883
Construct_productWBCnstr00010274
WBCnstr00019303
WBCnstr00035829
Microarray_results (36)
Expression_cluster (103)
Interaction (72)
Anatomy_functionWBbtf0086
WBbtf1049
Map_infoMapIIIPosition-0.951383Error0.006326
Well_ordered
PositivePositive_cloneC28A6
Y102E9Inferred_automaticallyFrom sequence, transcript, pseudogene data
NegativeNegative_cloneF37A4Author_evidenceDwyer ND
K07E12Author_evidenceDwyer ND
Mapping_dataMulti_point2055
2056
2057
2058
4976
5453
Pos_neg_data5983
ReferenceWBPaper00001786
WBPaper00002967
WBPaper00003063
WBPaper00003455
WBPaper00003680
WBPaper00003824
WBPaper00003894
WBPaper00003977
WBPaper00005511
WBPaper00006088
WBPaper00006103
WBPaper00011634
WBPaper00014235
WBPaper00016863
WBPaper00017266
WBPaper00017490
WBPaper00017682
WBPaper00017999
WBPaper00019212
WBPaper00019253
WBPaper00020756
WBPaper00021745
WBPaper00022218
WBPaper00024803
WBPaper00025051
WBPaper00025243
WBPaper00025472
WBPaper00027202
WBPaper00028172
WBPaper00029015
WBPaper00030504
WBPaper00031788
WBPaper00031936
WBPaper00038491
WBPaper00040144
WBPaper00042233
WBPaper00044965
WBPaper00044991
WBPaper00055090
WBPaper00060850
RemarkData extracted from Dwyer et al. (1998)
MethodGene