WormBase Tree Display for Gene: WBGene00001122
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WBGene00001122 | SMap | S_parent | Sequence | F46F6 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | dyf-6 | Person_evidence | WBPerson252 | |||
Sequence_name | F46F6.4 | ||||||
Molecular_name (13) | |||||||
Other_name | CELE_F46F6.4 | Accession_evidence | NDB | BX284606 | |||
Public_name | dyf-6 | ||||||
DB_info | Database | WormQTL | gene | WBGene00001122 | |||
WormFlux | gene | WBGene00001122 | |||||
NDB | locus_tag | CELE_F46F6.4 | |||||
Panther | gene | CAEEL|WormBase=WBGene00001122|UniProtKB=Q0G838 | |||||
family | PTHR13376 | ||||||
NCBI | gene | 3565899 | |||||
RefSeq | protein | NM_001083298.2 | |||||
NM_001392834.1 | |||||||
NM_001083299.3 | |||||||
NM_001083301.4 | |||||||
SwissProt | UniProtAcc | Q0G838 | |||||
TREEFAM | TREEFAM_ID | TF314221 | |||||
UniProt_GCRP | UniProtAcc | Q0G838 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Acquires_merge | WBGene00009795 | ||||||
WBGene00009794 | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | dyf | ||||||
Allele (113) | |||||||
Legacy_information | [Herman RK] Defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3(m175), ME4(mn346) | ||||||
[C.elegansII] m175 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3(m175), ME4(mn346) OA1: mn346mut. [Starich et al. 1995] | |||||||
Complementation_data | [Herman RK] dyf-6(m175) complements dyf-7(m537), dyf-12(sa127), daf-12(m20) and vab-3(e648) with respect to dye filling. dyf-6(mn346) complements dyf-12(sa122) and vab-3(e648) with respect to dye filling. | ||||||
Strain | WBStrain00034381 | ||||||
WBStrain00034417 | |||||||
WBStrain00036858 | |||||||
WBStrain00036887 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (18) | |||||||
Ortholog (40) | |||||||
Structured_description | Concise_description | dyf-6 encodes several proteins that, while novel, contain orthologs in Drosophila and mammals; during development, dyf-6 activity is essential for establishing the normal dendritic length of the amphid and phasmid chemosensory neurons; a DYF-6::GFP reporter is expressed in amphid and phasmid neurons where it: 1) localizes to dendritic bodies and endings as well as to cell bodies, and 2) appears to undergo intraflagellar transport (IFT); DYF-6::GFP is also seen in hypodermal cells and in additional neurons, including inner labial neurons and a lateral neuron in the vicinity of PDE; genetic mosaic analyses indicate that dyf-6 functions autonomously at the level of the amphid dendritic bundle to regulate proper dendritic morphology. | Paper_evidence | WBPaper00002087 | |||
WBPaper00027360 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 23 Feb 2007 00:00:00 | ||||||
Automated_description | Involved in intraciliary transport and non-motile cilium assembly. Located in dendrite and neuronal cell body. Expressed in ciliated neurons and hypodermis. Is an ortholog of human IFT46 (intraflagellar transport 46). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F46F6.4a | |||||
F46F6.4b | |||||||
F46F6.4c | |||||||
F46F6.4d | |||||||
Corresponding_CDS_history | F46F6.4:wp163 | ||||||
Corresponding_transcript | F46F6.4a.1 | ||||||
F46F6.4b.1 | |||||||
F46F6.4c.1 | |||||||
F46F6.4c.2 | |||||||
F46F6.4d.1 | |||||||
Other_sequence | CR03480 | ||||||
CRC02533_1 | |||||||
Oden_isotig25770 | |||||||
JI479891.1 | |||||||
Associated_feature (14) | |||||||
Experimental_info | RNAi_result | WBRNAi00015120 | Inferred_automatically | RNAi_primary | |||
WBRNAi00047566 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00047565 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr4523 | ||||||
Expr1017659 | |||||||
Expr1030717 | |||||||
Expr1151403 | |||||||
Expr2011136 | |||||||
Expr2029372 | |||||||
Drives_construct | WBCnstr00012076 | ||||||
WBCnstr00016048 | |||||||
WBCnstr00037074 | |||||||
Construct_product | WBCnstr00012076 | ||||||
WBCnstr00037074 | |||||||
Microarray_results (33) | |||||||
Expression_cluster (125) | |||||||
Interaction (32) | |||||||
Map_info | Map | X | Position | 2.16901 | Error | 0.003805 | |
Positive | Positive_clone | F46F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 3090 | |||||
3091 | |||||||
Pos_neg_data | 8324 | ||||||
8329 | |||||||
8325 | |||||||
Reference | WBPaper00002087 | ||||||
WBPaper00002948 | |||||||
WBPaper00002967 | |||||||
WBPaper00004405 | |||||||
WBPaper00006516 | |||||||
WBPaper00019220 | |||||||
WBPaper00026348 | |||||||
WBPaper00027360 | |||||||
WBPaper00029015 | |||||||
WBPaper00029016 | |||||||
WBPaper00029131 | |||||||
WBPaper00031170 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00055368 | |||||||
Method | Gene |