WormBase Tree Display for Gene: WBGene00000458
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| WBGene00000458 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
|---|---|---|---|---|---|---|---|
| Identity (6) | |||||||
| Gene_info | Biotype | SO:0001217 | |||||
| Gene_class | ceh | ||||||
| Allele (260) | |||||||
| Strain | WBStrain00003219 | ||||||
| WBStrain00024200 | |||||||
| WBStrain00024201 | |||||||
| WBStrain00031536 | |||||||
| WBStrain00048942 | |||||||
| WBStrain00055073 | |||||||
| RNASeq_FPKM (74) | |||||||
| GO_annotation (29) | |||||||
| Ortholog (38) | |||||||
| Paralog (20) | |||||||
| Structured_description | Concise_description | ceh-37 encodes one of three C. elegans proteins with an OTX-like homeodomain; however, CEH-37 lacks other domains found in OTX proteins, and the CEH-37 homeodomain is predicted to resemble the Myb domain of telomere-binding proteins; CEH-37 binds the telomeric sequence 'TTAGGC' if it is repeated at least 1.5 times, and is mainly localized to the telomere in vivo; ceh-37 mutants have a weak increase in chromosomal nondisjunction; CEH-37 is involved in specifying some aspects of the AWB olfactory neuron fate, such as expression of an AWB-specific odorant receptor and a LIM-class homeodomain protein, LIM-4; CEH-37 is expressed broadly in the early embryo, while in larvae and adults it is expressed solely in the excretory cell. | Paper_evidence | WBPaper00006000 | |||
| WBPaper00010611 | |||||||
| WBPaper00017043 | |||||||
| WBPaper00023311 | |||||||
| Curator_confirmed | WBPerson1843 | ||||||
| WBPerson480 | |||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
| Automated_description | Enables DNA binding activity, bending and double-stranded telomeric DNA binding activity. Involved in neuron fate specification; olfactory behavior; and regulation of transcription by RNA polymerase II. Located in chromosome, telomeric region. Expressed in several structures, including ABarpaap; dorsal nerve cord; excretory cell; head muscle; and head neurons. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Is an ortholog of human CRX (cone-rod homeobox). | Paper_evidence | WBPaper00065943 | ||||
| Curator_confirmed | WBPerson324 | ||||||
| WBPerson37462 | |||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
| Disease_info | Potential_model | DOID:0110333 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2383) | ||
| DOID:0111005 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2383) | ||||
| Molecular_info | Corresponding_CDS | C37E2.5a | |||||
| C37E2.5b | |||||||
| C37E2.5c | |||||||
| C37E2.5d | |||||||
| Corresponding_transcript | C37E2.5a.1 | ||||||
| C37E2.5b.1 | |||||||
| C37E2.5c.1 | |||||||
| C37E2.5d.1 | |||||||
| Other_sequence | ACC33504_1 | ||||||
| OOC03311_1 | |||||||
| Oden_isotig21898 | |||||||
| JI175634.1 | |||||||
| PPC21066_1 | |||||||
| JI170763.1 | |||||||
| ES564168.1 | |||||||
| EX559356.1 | |||||||
| Associated_feature (20) | |||||||
| Transcription_factor | WBTranscriptionFactor000475 | ||||||
| Experimental_info | RNAi_result | WBRNAi00107118 | Inferred_automatically | RNAi_primary | |||
| WBRNAi00106222 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00090702 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00029643 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00042117 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00011722 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern (14) | |||||||
| Drives_construct | WBCnstr00001666 | ||||||
| WBCnstr00003694 | |||||||
| WBCnstr00010926 | |||||||
| WBCnstr00012613 | |||||||
| WBCnstr00018499 | |||||||
| Construct_product | WBCnstr00010870 | ||||||
| WBCnstr00018499 | |||||||
| Microarray_results (20) | |||||||
| Expression_cluster (177) | |||||||
| Interaction (79) | |||||||
| Map_info | Map | X | Position | 16.6652 | Error | 0.001448 | |
| Positive | Positive_clone | C37E2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
| Mapping_data | Multi_point | 4209 | |||||
| 4254 | |||||||
| Pseudo_map_position | |||||||
| Reference | WBPaper00006000 | ||||||
| WBPaper00006146 | |||||||
| WBPaper00006241 | |||||||
| WBPaper00006397 | |||||||
| WBPaper00006457 | |||||||
| WBPaper00010043 | |||||||
| WBPaper00010212 | |||||||
| WBPaper00010721 | |||||||
| WBPaper00015440 | |||||||
| WBPaper00017043 | |||||||
| WBPaper00018934 | |||||||
| WBPaper00019273 | |||||||
| WBPaper00019505 | |||||||
| WBPaper00023311 | |||||||
| WBPaper00024772 | |||||||
| WBPaper00026069 | |||||||
| WBPaper00026818 | |||||||
| WBPaper00027299 | |||||||
| WBPaper00027309 | |||||||
| WBPaper00027473 | |||||||
| WBPaper00029015 | |||||||
| WBPaper00029400 | |||||||
| WBPaper00031936 | |||||||
| WBPaper00033331 | |||||||
| WBPaper00034710 | |||||||
| WBPaper00037005 | |||||||
| WBPaper00038491 | |||||||
| WBPaper00039443 | |||||||
| WBPaper00044622 | |||||||
| WBPaper00055090 | |||||||
| WBPaper00060123 | |||||||
| WBPaper00062913 | |||||||
| WBPaper00064718 | |||||||
| WBPaper00066332 | |||||||
| Remark | [Burglin T] registered gene name | ||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
| Method | Gene |
