drh-2 was identified, along with drh-1, as a gene that can encode a protein with similarity to DExH-box helicases; drh-2, however, is classified by WB as a pseudogene because it has two frameshifts, based on EST and RNASeq alignments; the first frameshift occurs in exon 4 and the second occurs in exon 8 of the current WB gene structure; drh-2 appears to be the first gene in an operon (CEOP4647) followed by drh-1 and nstp-2.
Enriched in intestine; muscle cell; and neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on proteomic; microarray; and RNA-seq studies. Is affected by twelve chemicals including rotenone; levamisole; and Psoralens based on RNA-seq and microarray studies.