cars-1 encodes a predicted cytoplasmic cysteinyl-tRNA synthetase (CysRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of cysteine to its cognate tRNA and is thus required for protein biosynthesis; CARS-1 is essential for embryonic and larval development, and is required for molting and a normal rate of postembryonic development.
Predicted to enable ATP binding activity and cysteine-tRNA ligase activity. Predicted to be involved in cysteinyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Is an ortholog of human CARS1 (cysteinyl-tRNA synthetase 1).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.