WormBase Tree Display for Gene: WBGene00000182
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WBGene00000182 | SMap | S_parent | Sequence | B0336 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | arf-1 | |||||||
Sequence_name | B0336.2 | ||||||||
Molecular_name | B0336.2 | ||||||||
B0336.2.1 | |||||||||
CE00696 | |||||||||
B0336.2.2 | |||||||||
Other_name | ARF/1 | ||||||||
arf-1.2 | |||||||||
CELE_B0336.2 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | arf-1 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 05 Nov 2004 15:32:14 | WBPerson2970 | Name_change | CGC_name | arf-1.2 | ||||
3 | 10 Sep 2020 13:24:17 | WBPerson1983 | Name_change | CGC_name | arf-1 | ||||
Other_name | arf-1.2 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | arf | ||||||||
Allele (33) | |||||||||
Legacy_information | [C.elegansII] NMK. Encodes 181 aa predicted class I ARF. [CGC, MQ] | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (22) | |||||||||
Contained_in_operon | CEOP3332 | ||||||||
Ortholog (45) | |||||||||
Paralog | WBGene00000180 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00000183 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000189 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000193 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000184 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000187 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000190 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000188 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00000192 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00001358 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00012132 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00021349 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00021841 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00022678 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | arf-1.2 encodes an ADP-ribosylation factor homolog required in vivo for embryonic development, fertility, locomotion, vulval development, and cuticular synthesis; ARF proteins are N-myristoylated GTPases that regulate membrane traffic and the actin cytoskeleton, and that activate both phospholipase D1 (PLD1) and phosphatidylinositol 4-phosphate 5-kinase. | Paper_evidence | WBPaper00012958 | |||||
WBPaper00013160 | |||||||||
WBPaper00015195 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 16 Jul 2007 00:00:00 | ||||||||
Automated_description | Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis. Located in endoplasmic reticulum. Expressed in pharyngeal muscle cell; uterus; ventral nerve cord; and vulval precursor cell. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human ARF1 (ADP ribosylation factor 1) and ARF3 (ADP ribosylation factor 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0050454 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:652) | ||||
Molecular_info | Corresponding_CDS | B0336.2 | |||||||
Corresponding_transcript | B0336.2.1 | ||||||||
B0336.2.2 | |||||||||
Other_sequence (178) | |||||||||
Associated_feature (13) | |||||||||
Experimental_info | RNAi_result (38) | ||||||||
Expr_pattern | Chronogram1686 | ||||||||
Expr3149 | |||||||||
Expr4834 | |||||||||
Expr5055 | |||||||||
Expr15679 | |||||||||
Expr1028066 | |||||||||
Expr1030106 | |||||||||
Expr1143124 | |||||||||
Expr2009391 | |||||||||
Expr2027627 | |||||||||
Drives_construct | WBCnstr00002999 | ||||||||
WBCnstr00011177 | |||||||||
WBCnstr00012265 | |||||||||
WBCnstr00019869 | |||||||||
WBCnstr00037680 | |||||||||
WBCnstr00042476 | |||||||||
Construct_product | WBCnstr00008785 | ||||||||
WBCnstr00008786 | |||||||||
WBCnstr00019869 | |||||||||
WBCnstr00037680 | |||||||||
WBCnstr00042476 | |||||||||
Microarray_results (26) | |||||||||
Expression_cluster (132) | |||||||||
Interaction (182) | |||||||||
Map_info (4) | |||||||||
Reference (37) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
This gene was previously assigned the CGC name arf-1. It has been re-assigned to arf-1.2 | Curator_confirmed | WBPerson2970 | |||||||
Method | Gene |