WormBase Tree Display for Gene: WBGene00000182
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WBGene00000182 | SMap | S_parent | Sequence | B0336 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | arf | ||||||
Allele (33) | |||||||
Legacy_information | [C.elegansII] NMK. Encodes 181 aa predicted class I ARF. [CGC, MQ] | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (22) | |||||||
Contained_in_operon | CEOP3332 | ||||||
Ortholog (45) | |||||||
Paralog | WBGene00000180 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00000183 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000189 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000193 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000184 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000187 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000190 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00000188 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00000192 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00001358 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00012132 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00021349 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00021841 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00022678 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | arf-1.2 encodes an ADP-ribosylation factor homolog required in vivo for embryonic development, fertility, locomotion, vulval development, and cuticular synthesis; ARF proteins are N-myristoylated GTPases that regulate membrane traffic and the actin cytoskeleton, and that activate both phospholipase D1 (PLD1) and phosphatidylinositol 4-phosphate 5-kinase. | Paper_evidence | WBPaper00012958 | |||
WBPaper00013160 | |||||||
WBPaper00015195 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 16 Jul 2007 00:00:00 | ||||||
Automated_description | Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis. Located in endoplasmic reticulum. Expressed in pharyngeal muscle cell; uterus; ventral nerve cord; and vulval precursor cell. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human ARF1 (ADP ribosylation factor 1) and ARF3 (ADP ribosylation factor 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0050454 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:652) | ||
Molecular_info | Corresponding_CDS | B0336.2 | |||||
Corresponding_transcript | B0336.2.1 | ||||||
B0336.2.2 | |||||||
Other_sequence (178) | |||||||
Associated_feature (13) | |||||||
Experimental_info | RNAi_result (38) | ||||||
Expr_pattern | Chronogram1686 | ||||||
Expr3149 | |||||||
Expr4834 | |||||||
Expr5055 | |||||||
Expr15679 | |||||||
Expr1028066 | |||||||
Expr1030106 | |||||||
Expr1143124 | |||||||
Expr2009391 | |||||||
Expr2027627 | |||||||
Drives_construct | WBCnstr00002999 | ||||||
WBCnstr00011177 | |||||||
WBCnstr00012265 | |||||||
WBCnstr00019869 | |||||||
WBCnstr00037680 | |||||||
WBCnstr00042476 | |||||||
Construct_product | WBCnstr00008785 | ||||||
WBCnstr00008786 | |||||||
WBCnstr00019869 | |||||||
WBCnstr00037680 | |||||||
WBCnstr00042476 | |||||||
Microarray_results (26) | |||||||
Expression_cluster (132) | |||||||
Interaction (182) | |||||||
Map_info | Map | III | Position | -1.44726 | Error | 0.000356 | |
Positive | Positive_clone | B0336 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
NM#G4 | |||||||
Mapping_data | Multi_point | 4788 | |||||
5049 | |||||||
Pseudo_map_position | |||||||
Reference (37) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
This gene was previously assigned the CGC name arf-1. It has been re-assigned to arf-1.2 | Curator_confirmed | WBPerson2970 | |||||
Method | Gene |