WormBase Tree Display for Gene: WBGene00018734
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| WBGene00018734 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | Sequence_name | F53A10.2 | |||||||
| Molecular_name (22) | |||||||||
| Other_name | CELE_F53A10.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | F53A10.2 | ||||||||
| DB_info | Database | AceView | gene | 2B519 | |||||
| WormQTL | gene | WBGene00018734 | |||||||
| WormFlux | gene | WBGene00018734 | |||||||
| NDB | locus_tag | CELE_F53A10.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00018734|UniProtKB=H2L055 | |||||||
| family | PTHR15711 | ||||||||
| NCBI | gene | 173502 | |||||||
| RefSeq | protein | NM_001322703.3 | |||||||
| NM_001322701.3 | |||||||||
| NM_001393000.1 | |||||||||
| NM_001393001.1 | |||||||||
| NM_001322702.3 | |||||||||
| NM_001027019.3 | |||||||||
| TrEMBL | UniProtAcc | A0A131MBF2 | |||||||
| H2L055 | |||||||||
| A0A131MCP2 | |||||||||
| A0A131MBM3 | |||||||||
| Q8IA84 | |||||||||
| Q965M4 | |||||||||
| UniProt_GCRP | UniProtAcc | H2L055 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 29 Nov 2004 17:10:33 | WBPerson2970 | Event | Acquires_merge | WBGene00018733 | ||||
| Acquires_merge | WBGene00018733 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (847) | |||||||||
| Strain | WBStrain00055198 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00001998 | ||||||||
| 00001999 | |||||||||
| 00002000 | |||||||||
| 00022854 | |||||||||
| 00022855 | |||||||||
| 00123774 | |||||||||
| 00123775 | |||||||||
| 00123776 | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00012100 | Caenorhabditis elegans | From_analysis (3) | ||||||
| Structured_description | Concise_description | F53A10.2 encodes a Rap1GAP homolog; a region of F53A10.2 encompassing one GoLoco motif specifically binds GOA-1 in yeast two-hybrid assays, and also binds itself; F53A10.2 is expressed in hypodermal seam cells, various neurons, and intestinal cells; F53A10.2 has no obvious function or phenotype in RNAi assays, whether in a normal background or in goa-1(-) or goa-1(gf) mutant backgrounds. | Paper_evidence | WBPaper00006194 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytoplasm. Expressed in intestine; neurons; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; endocrine gland cancer (multiple); and myelodysplastic syndrome. Is an ortholog of human RAP1GAP (RAP1 GTPase activating protein) and RAP1GAP2 (RAP1 GTPase activating protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3969 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||
| DOID:3312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
| DOID:0050908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
| DOID:1909 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
| DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
| DOID:1312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
| Molecular_info | Corresponding_CDS | F53A10.2a | |||||||
| F53A10.2b | |||||||||
| F53A10.2c | |||||||||
| F53A10.2d | |||||||||
| F53A10.2e | |||||||||
| F53A10.2f | |||||||||
| Corresponding_transcript | F53A10.2a.1 | ||||||||
| F53A10.2b.1 | |||||||||
| F53A10.2b.2 | |||||||||
| F53A10.2b.3 | |||||||||
| F53A10.2b.4 | |||||||||
| F53A10.2b.5 | |||||||||
| F53A10.2c.1 | |||||||||
| F53A10.2d.1 | |||||||||
| F53A10.2e.1 | |||||||||
| F53A10.2f.1 | |||||||||
| Other_sequence | Tcir_isotig12459 | ||||||||
| AE04696 | |||||||||
| MJ02003 | |||||||||
| JI467716.1 | |||||||||
| HC00767 | |||||||||
| MH04640 | |||||||||
| MIC04718_1 | |||||||||
| MAC00142_1 | |||||||||
| MA00779 | |||||||||
| HC06736 | |||||||||
| PT01479 | |||||||||
| ACC05933_1 | |||||||||
| AYC02476_1 | |||||||||
| GO239802.1 | |||||||||
| Oden_isotig24142 | |||||||||
| HG10283 | |||||||||
| MJ03489 | |||||||||
| HCC03697_1 | |||||||||
| EY461975.1 | |||||||||
| AE03716 | |||||||||
| Dviv_isotig23205 | |||||||||
| Acan_isotig07633 | |||||||||
| JI166202.1 | |||||||||
| OFC01018_1 | |||||||||
| PTC00947_1 | |||||||||
| MJC01027_1 | |||||||||
| Oden_isotig21869 | |||||||||
| HC00779 | |||||||||
| Name_isotig02662 | |||||||||
| CJC08339_1 | |||||||||
| JI479038.1 | |||||||||
| HCC05799_1 | |||||||||
| HCC05501_1 | |||||||||
| Oden_isotig20399 | |||||||||
| CBC09017_1 | |||||||||
| OF01531 | |||||||||
| EY473188.1 | |||||||||
| MH10198 | |||||||||
| MA00713 | |||||||||
| ACC23993_1 | |||||||||
| ACC27450_1 | |||||||||
| HG10096 | |||||||||
| MHC08554_1 | |||||||||
| CRC01421_1 | |||||||||
| CR10554 | |||||||||
| JI165965.1 | |||||||||
| HGC01075_1 | |||||||||
| OOC00850_1 | |||||||||
| Associated_feature (40) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00032647 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00063378 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015207 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00063366 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020851 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032648 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048037 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015447 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048036 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048038 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2756 | ||||||||
| Expr1015564 | |||||||||
| Expr1038064 | |||||||||
| Expr1151853 | |||||||||
| Expr2004017 | |||||||||
| Expr2022239 | |||||||||
| Drives_construct | WBCnstr00010936 | ||||||||
| Construct_product | WBCnstr00010936 | ||||||||
| Microarray_results (40) | |||||||||
| Expression_cluster (105) | |||||||||
| Interaction (40) | |||||||||
| Map_info | Positive | Positive_clone | F53A10 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | II | -15.5618 | |||||||
| Reference | WBPaper00036647 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
