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WormBase Tree Display for Gene: WBGene00011906

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Name Class

WBGene00011906SMapS_parentSequenceT22A3
IdentityVersion2
NameCGC_namehsp-12.1Person_evidenceWBPerson36
Sequence_nameT22A3.2
Molecular_nameT22A3.2a
T22A3.2a.1
CE13914
T22A3.2b
CE40519
T22A3.2b.1
Other_nameCELE_T22A3.2Accession_evidenceNDBBX284601
Public_namehsp-12.1
DB_infoDatabaseWormQTLgeneWBGene00011906
WormFluxgeneWBGene00011906
NDBlocus_tagCELE_T22A3.2
PanthergeneCAEEL|WormBase=WBGene00011906|UniProtKB=G5EE65
familyPTHR45640
NCBIgene188710
RefSeqproteinNM_001083144.2
NM_001083145.4
TrEMBLUniProtAccG5EE65
O01263
UniProt_GCRPUniProtAccG5EE65
OMIMgene123580
123590
602195
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
228 Jul 2004 13:52:33WBPerson1971Name_changeCGC_namehsp-12.1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhsp
Allele (21)
StrainWBStrain00033275
RNASeq_FPKM (74)
GO_annotation00015479
00015480
00015481
00015482
00015483
00015484
00015485
Ortholog (46)
Paralog (17)
Structured_descriptionConcise_descriptionhsp-12.1 encodes a member of the small heat shock family of proteins.Paper_evidenceWBPaper00013029
Curator_confirmedWBPerson1843
Date_last_updated02 Mar 2007 00:00:00
Automated_descriptionPredicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in striated muscle dense body. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease axonal type 2F; cataract (multiple); and myofibrillar myopathy (multiple). Is an ortholog of human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB6 (heat shock protein family B (small) member 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (11)
Molecular_infoCorresponding_CDS (2)
Corresponding_transcriptT22A3.2a.1
T22A3.2b.1
Other_sequenceFG619378.1
MI01124
MI04039
FG619497.1
XI01250
FG619499.1
XI00110
ASC00177_1
FG619483.1
XIC00008_1
JI215767.1
FG619467.1
XI00113
FG619509.1
RSC03934_1
XI01055
FG619351.1
TX00528
MJC04657_1
MH00627
MI02651
XI00118
CN477965.1
PTC04428_1
XIC00705_1
FG619486.1
MIC00522_1
TCC00429_1
FG619465.1
FG619474.1
XI00132
XI00063
MHC01208_1
BXC04219_1
FG619498.1
RSC04467_1
XI02093
RS11386
MJC00040_1
FG619478.1
MI00454
MJC00040_2
XI01296
PT04899
XIC00848_1
MAC01324_1
XI01287
BUC00860_1
XI02310
FG619396.1
AS02704
MJ00843
AS01410
FG619496.1
XI00809
MP00626
FG619501.1
JO473342.1
ALC00221_1
CJC14150_1
XI00097
RS05873
XI00103
ASC17546_1
PT04465
ASC17449_1
CN477412.1
MPC00399_1
BU585661.1
FG619482.1
XI00108
CN477974.1
FG619473.1
MP01693
FG619512.1
FG619479.1
FG619415.1
XI00078
MIC00522_2
FG619513.1
MI00049
MA01997
Associated_featureWBsf655318
WBsf985040
WBsf220257
WBsf220258
WBsf220259
Experimental_infoRNAi_resultWBRNAi00116981Inferred_automaticallyRNAi_primary
WBRNAi00035777Inferred_automaticallyRNAi_primary
WBRNAi00053771Inferred_automaticallyRNAi_primary
WBRNAi00076696Inferred_automaticallyRNAi_primary
WBRNAi00106376Inferred_automaticallyRNAi_primary
WBRNAi00004252Inferred_automaticallyRNAi_primary
Expr_patternExpr9395
Expr15506
Expr1021401
Expr1035252
Expr1157322
Expr2012612
Expr2030848
Drives_constructWBCnstr00030294
WBCnstr00042197
Construct_productWBCnstr00013960
WBCnstr00030294
WBCnstr00042197
AntibodyWBAntibody00003010
Microarray_results (20)
Expression_cluster (170)
Interaction (48)
Map_infoMapIPosition5.05599Error6.2e-05
PositivePositive_cloneT22A3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene