WormBase Tree Display for Gene: WBGene00004270
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WBGene00004270 | SMap | S_parent | Sequence | T25G12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | rab-6.2 | Person_evidence | WBPerson451 | |||||
Sequence_name | T25G12.4 | ||||||||
Molecular_name | T25G12.4 | ||||||||
T25G12.4.1 | |||||||||
CE07541 | |||||||||
Other_name | CELE_T25G12.4 | Accession_evidence | NDB | BX284606 | |||||
Public_name | rab-6.2 | ||||||||
DB_info | Database | AceView | gene | XR837 | |||||
WormQTL | gene | WBGene00004270 | |||||||
WormFlux | gene | WBGene00004270 | |||||||
NDB | locus_tag | CELE_T25G12.4 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004270|UniProtKB=Q22782 | |||||||
family | PTHR24073 | ||||||||
NCBI | gene | 181759 | |||||||
RefSeq | protein | NM_078389.7 | |||||||
SwissProt | UniProtAcc | Q22782 | |||||||
TREEFAM | TREEFAM_ID | TF300803 | |||||||
UniProt_GCRP | UniProtAcc | Q22782 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rab | ||||||||
Allele (29) | |||||||||
Strain | WBStrain00001717 | ||||||||
WBStrain00001718 | |||||||||
WBStrain00037087 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (36) | |||||||||
Ortholog (50) | |||||||||
Paralog (32) | |||||||||
Structured_description | Concise_description | rab-6.2 encodes a small, monomeric Rab GTPase that is most closely related to the Drosophila and mammalian Rab6 GTPases; by homology, RAB-6.2 is predicted to function in the regulation of intracellular membrane trafficking; RNAi experiments indicate that rab-6.2 is required redundantly with rab-6.1 for normal embryonic development and reproduction; a RAB-6.2::GFP fusion protein localizes to the Golgi cisternae; RAB-6.2 physically interacts with VPS-52, a GARP (Golgi associated retrograde protein) complex subunit, in vivo. | Paper_evidence | WBPaper00030808 | |||||
WBPaper00038455 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 13 Jan 2012 00:00:00 | ||||||||
Automated_description | Enables GTP binding activity. Involved in several processes, including early endosome to Golgi transport; positive regulation of feeding behavior; and protein stabilization. Located in Golgi trans cisterna. Expressed in several structures, including coelomocyte; command interneuron; gonad; pharynx; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family) and RAB6B (RAB6B, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T25G12.4 | |||||||
Corresponding_transcript | T25G12.4.1 | ||||||||
Other_sequence | FC552429.1 | ||||||||
CGC00184_1 | |||||||||
Dviv_isotig09999 | |||||||||
Name_isotig00947 | |||||||||
RSC00339_1 | |||||||||
Acan_isotig23108 | |||||||||
XIC04069_1 | |||||||||
FC540760.1 | |||||||||
Dviv_isotig10000 | |||||||||
Acan_isotig08046 | |||||||||
SS00847 | |||||||||
JI181094.1 | |||||||||
CJC01727_1 | |||||||||
SSC00887_1 | |||||||||
Acan_isotig07097 | |||||||||
Oden_isotig17608 | |||||||||
ES273449.1 | |||||||||
CBC01067_1 | |||||||||
ACC25469_1 | |||||||||
PVC03452_1 | |||||||||
EY464924.1 | |||||||||
FC548096.1 | |||||||||
Hbac_isotig05173 | |||||||||
AW499037.1 | |||||||||
BMC03608_1 | |||||||||
TSC04316_1 | |||||||||
BXC00854_1 | |||||||||
FC555628.1 | |||||||||
HG03457 | |||||||||
EX558563.1 | |||||||||
Oden_isotig20320 | |||||||||
BUC02240_1 | |||||||||
EY470300.1 | |||||||||
PPC09159_1 | |||||||||
TSC01560_1 | |||||||||
HGC02391_1 | |||||||||
Dviv_isotig09998 | |||||||||
EY461250.1 | |||||||||
Tcir_isotig07261 | |||||||||
EX555508.1 | |||||||||
TS03082 | |||||||||
Dviv_isotig09997 | |||||||||
BXC03559_1 | |||||||||
Acan_isotig07098 | |||||||||
FC552433.1 | |||||||||
TS00113 | |||||||||
ACC04169_1 | |||||||||
XI05480 | |||||||||
EW742648.1 | |||||||||
OVC03077_1 | |||||||||
Associated_feature | WBsf655243 | ||||||||
WBsf1008841 | |||||||||
WBsf1024977 | |||||||||
WBsf236886 | |||||||||
WBsf236887 | |||||||||
WBsf236888 | |||||||||
WBsf236889 | |||||||||
WBsf236890 | |||||||||
Experimental_info | RNAi_result (11) | ||||||||
Expr_pattern (11) | |||||||||
Drives_construct | WBCnstr00002541 | ||||||||
WBCnstr00002542 | |||||||||
WBCnstr00014399 | |||||||||
WBCnstr00015514 | |||||||||
WBCnstr00018181 | |||||||||
WBCnstr00035597 | |||||||||
Construct_product | WBCnstr00008290 | ||||||||
WBCnstr00014399 | |||||||||
WBCnstr00015121 | |||||||||
WBCnstr00015514 | |||||||||
WBCnstr00019185 | |||||||||
WBCnstr00035597 | |||||||||
Microarray_results (20) | |||||||||
Expression_cluster (151) | |||||||||
Interaction (108) | |||||||||
Map_info | Map | X | Position | 24.0866 | Error | 0.000393 | |||
Positive | Positive_clone | T25G12 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point (3) | ||||||||
Pseudo_map_position | |||||||||
Reference (24) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |