WormBase Tree Display for Gene: WBGene00004020
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| WBGene00004020 | SMap | S_parent | Sequence | EGAP2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pho-1 | Person_evidence | WBPerson411 | |||||
| Sequence_name | EGAP2.3 | ||||||||
| Molecular_name | EGAP2.3 | ||||||||
| EGAP2.3.1 | |||||||||
| CE04325 | |||||||||
| Other_name | CELE_EGAP2.3 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | pho-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pho | ||||||||
| Allele (44) | |||||||||
| Legacy_information | [C.elegansII] ca101 : electrophoretic variant in major acidphosphatase, no other phenotype. NA1. Purified protein is homodimeric glycoprotein,55kD subunit; activity detected at luminal edge of most gut cells, but not 6 most anterior. [Beh et al. 1991; JM] | ||||||||
| [Beh CT, McGhee JD] ca101 leads to electrophoretic variant in major acid phosphatase, no other phenotype. NA1. Purified protein is homodimeric glycoprotein, 55kD subunit, activity detected at luminal edge of most gut cells, but not 6 most anterior. | |||||||||
| Strain (3) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00063393 | ||||||||
| 00063394 | |||||||||
| 00063395 | |||||||||
| 00063396 | |||||||||
| 00063397 | |||||||||
| 00063398 | |||||||||
| 00063399 | |||||||||
| 00063400 | |||||||||
| Ortholog (27) | |||||||||
| Paralog (23) | |||||||||
| Structured_description | Concise_description | pho-1 encodes the major C. elegans intestinal acid phosphatase; PHO-1 may function redundantly with other acid phosphatases; PHO-1 intestinal expression appears to be positively regulated by CKI-1, a cyclin-dependent kinase inhibitor, and negatively regulated by POP-1, a TCF/LEF transcription factor; PHO-1 is expressed along the intestinal brush border in all gut cells except the most anterior int-1 and int-2 cells, beginning at the three-fold stage of embryogenesis. | Paper_evidence | WBPaper00001454 | |||||
| WBPaper00005295 | |||||||||
| WBPaper00017091 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 27 Mar 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Located in membrane raft. Expressed in intestine. Used to study obesity. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00061889 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 28 Jun 2022 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00001252 | ||||||||
| Molecular_info | Corresponding_CDS | EGAP2.3 | |||||||
| Corresponding_transcript | EGAP2.3.1 | ||||||||
| Other_sequence | HBC02467_1 | ||||||||
| FD515414.1 | |||||||||
| Oden_isotig05374 | |||||||||
| FK802508.1 | |||||||||
| Oden_isotig05378 | |||||||||
| CR09154 | |||||||||
| Oden_isotig05382 | |||||||||
| ES744292.1 | |||||||||
| Oden_isotig05375 | |||||||||
| Oden_isotig05381 | |||||||||
| Oden_isotig19579 | |||||||||
| CRC03535_1 | |||||||||
| Oden_isotig05377 | |||||||||
| HC05394 | |||||||||
| CR09153 | |||||||||
| AY134440.1 | |||||||||
| HCC01432_1 | |||||||||
| EX916124.1 | |||||||||
| CSC01245_1 | |||||||||
| EX012183.1 | |||||||||
| Oden_isotig05380 | |||||||||
| Dviv_isotig23693 | |||||||||
| EX014332.1 | |||||||||
| MI02734 | |||||||||
| EX913884.1 | |||||||||
| Oden_isotig05379 | |||||||||
| Acan_isotig10859 | |||||||||
| Hbac_isotig03456 | |||||||||
| Oden_isotig05376 | |||||||||
| Associated_feature | WBsf650050 | ||||||||
| WBsf650051 | |||||||||
| WBsf665523 | |||||||||
| WBsf982352 | |||||||||
| WBsf982353 | |||||||||
| WBsf223018 | |||||||||
| WBsf223019 | |||||||||
| WBsf223020 | |||||||||
| WBsf223021 | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Expr3212 | ||||||||
| Expr1027207 | |||||||||
| Expr1031925 | |||||||||
| Expr1147694 | |||||||||
| Expr2014906 | |||||||||
| Expr2033142 | |||||||||
| Drives_construct | WBCnstr00000345 | ||||||||
| WBCnstr00035738 | |||||||||
| Construct_product | WBCnstr00035738 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (259) | |||||||||
| Interaction (67) | |||||||||
| Map_info | Map | II | Position | -1.84291 | Error | 0.018889 | |||
| Positive | Positive_clone | EGAP2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | 2_point | 7072 | |||||||
| 7073 | |||||||||
| 7074 | |||||||||
| Multi_point | 3635 | ||||||||
| 3636 | |||||||||
| 5004 | |||||||||
| 5035 | |||||||||
| Reference (19) | |||||||||
| Remark | Data extracted from Beh et al. (1991) | ||||||||
| Sequence connection from [McGhee JD] | |||||||||
| Method | Gene |
