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WormBase Tree Display for Gene: WBGene00002241

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Name Class

WBGene00002241SMapS_parentSequenceF10C2
IdentityVersion1
NameCGC_namekup-1Person_evidenceWBPerson71
Sequence_nameF10C2.2
Molecular_nameF10C2.2
F10C2.2.1
CE09306
Other_name (2)
Public_namekup-1
DB_infoDatabaseAceViewgene5M514
WormQTLgeneWBGene00002241
WormFluxgeneWBGene00002241
NDBlocus_tagCELE_F10C2.2
NCBIgene179651
RefSeqproteinNM_001392622.1
SwissProtUniProtAccP34705
UniProt_GCRPUniProtAccP34705
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:27WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkup
Allele (99)
Legacy_information[C.elegansII] NMK. Upstream in operon with kin-13. Encodes predicted 385 aa novel protein. Antibody stains nuclei of most cells. [Zorio et al. 1994; CR]
StrainWBStrain00035751
RNASeq_FPKM (74)
Contained_in_operonCEOP5312
Ortholog (27)
Structured_descriptionConcise_descriptionkup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known.Paper_evidenceWBPaper00001950
WBPaper00005493
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnriched in several structures, including AVK; MSaapaapa; accessory cell; anterior arcade cell; and g2 based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and gld-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF10C2.2
Corresponding_transcriptF10C2.2.1
Other_sequenceL12247
JI170261.1
CBC05838_1
Tcir_isotig23500
Oden_isotig06124
JI468182.1
JI241750.1
Oden_isotig06123
CRC07770_1
HCC00096_1
BMC10702_1
FG350055.1
Tcol_isotig02798
Tcol_isotig02800
JI169466.1
JI478692.1
MAC01048_1
Tcol_isotig16323
Tcol_isotig02797
JI167864.1
FG587702.1
MA01739
FG585700.1
PPC03490_1
JI253302.1
JI232403.1
CJC04662_1
HC05922
CJC10231_1
Hbac_isotig02636
FF679042.1
Dviv_isotig17594
JI178536.1
Acan_isotig09945
CRC10918_1
Tcol_isotig02796
HBC15345_1
FG352962.1
Tcol_isotig02799
OF01452
JI246280.1
JI241444.1
Associated_feature (30)
Experimental_infoRNAi_resultWBRNAi00044221Inferred_automaticallyRNAi_primary
WBRNAi00013038Inferred_automaticallyRNAi_primary
WBRNAi00085043Inferred_automaticallyRNAi_primary
Expr_patternExpr12857
Expr1021564
Expr1031316
Expr1148182
Expr2012983
Expr2031215
Drives_constructWBCnstr00022908
Microarray_results (20)
Expression_cluster (139)
InteractionWBInteraction000227835
WBInteraction000396019
WBInteraction000435475
WBInteraction000574965
WBInteraction000576308
Map_infoMapVPosition3.60848Error0.003861
PositivePositive_cloneF10C2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4470
4586
Pseudo_map_position
ReferenceWBPaper00001723
WBPaper00002006
WBPaper00005493
WBPaper00010944
WBPaper00015440
WBPaper00022096
WBPaper00031335
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene