WormBase Tree Display for Gene: WBGene00000879
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WBGene00000879 | SMap | S_parent | Sequence | Y75B12B | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cyn-3 | Person_evidence | WBPerson466 | |||||
Sequence_name | Y75B12B.5 | ||||||||
Molecular_name | Y75B12B.5 | ||||||||
Y75B12B.5.1 | |||||||||
CE20374 | |||||||||
Other_name | cyp-3 | Person_evidence | WBPerson466 | ||||||
CELE_Y75B12B.5 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | cyn-3 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 20 Sep 2004 16:20:03 | WBPerson1971 | Name_change | CGC_name | cyp-3 -> cyn-3 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cyn | ||||||||
Allele (28) | |||||||||
Legacy_information | [C.elegansII] NMK. Cyclophilin family, transspliced to SL1. YAC Y15F7. [TP] | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Contained_in_operon | CEOP5521 | ||||||||
Ortholog (54) | |||||||||
Paralog (18) | |||||||||
Structured_description | Concise_description | cyn-3 encodes an abundantly expressed cyclophilin A isoform with peptidyl-prolyl isomerase activity in vitro, which closely resembles the prototypical CypA and is thus likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; cyn-3 is exclusively expressed in the single anterior excretory cell, and is dispensable for viability and gross morphology in mass RNAi screens. | Paper_evidence | WBPaper00002472 | |||||
WBPaper00003820 | |||||||||
WBPaper00005654 | |||||||||
WBPaper00026884 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 20 Mar 2007 00:00:00 | ||||||||
Automated_description | Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in obsolete cell. Expressed in excretory system. Human ortholog(s) of this gene implicated in several diseases, including Bell's palsy; aggressive periodontitis; and gastrointestinal system cancer (multiple). Is an ortholog of human PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:4947 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||
DOID:9261 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
DOID:1474 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
DOID:526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
DOID:12506 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
Molecular_info | Corresponding_CDS | Y75B12B.5 | |||||||
Corresponding_transcript | Y75B12B.5.1 | ||||||||
Other_sequence | U31077 | ||||||||
HSC01591_1 | |||||||||
MC04529 | |||||||||
MJC03416_1 | |||||||||
ES410560.1 | |||||||||
AM743421.1 | |||||||||
RS07649 | |||||||||
GRC00341_1 | |||||||||
NB07599 | |||||||||
GO252597.1 | |||||||||
RSC02810_1 | |||||||||
BF599212.1 | |||||||||
BXC00733_1 | |||||||||
MJ00021 | |||||||||
AS03056 | |||||||||
SS00170 | |||||||||
Dviv_isotig16822 | |||||||||
JI625639.1 | |||||||||
EX014303.1 | |||||||||
AS02793 | |||||||||
AYC00194_2 | |||||||||
JI463044.1 | |||||||||
HCC00822_3 | |||||||||
MJC00401_1 | |||||||||
EG025472.1 | |||||||||
MA01922 | |||||||||
EH005629.1 | |||||||||
PT02146 | |||||||||
PE00078 | |||||||||
ES412014.1 | |||||||||
JI239671.1 | |||||||||
CBC14468_1 | |||||||||
HBC04166_1 | |||||||||
AW600038.1 | |||||||||
HC00013 | |||||||||
HS00290 | |||||||||
AI363650.1 | |||||||||
FG581023.1 | |||||||||
SRC05997_1 | |||||||||
ACC28445_1 | |||||||||
FE910012.1 | |||||||||
GR11923 | |||||||||
AI130079.1 | |||||||||
BMC02578_1 | |||||||||
Name_isotig06234 | |||||||||
Dviv_isotig16823 | |||||||||
EX911673.1 | |||||||||
MCC02593_1 | |||||||||
EX561321.1 | |||||||||
OVC01099_1 | |||||||||
PEC00274_1 | |||||||||
HG03434 | |||||||||
TS01412 | |||||||||
MIC09181_1 | |||||||||
BU086576.1 | |||||||||
JI257349.1 | |||||||||
AAC00250_1 | |||||||||
Tcir_isotig13512 | |||||||||
JI219938.1 | |||||||||
HC00039 | |||||||||
HCC00822_2 | |||||||||
BQ804066.1 | |||||||||
TS03678 | |||||||||
CBC05026_1 | |||||||||
MH02853 | |||||||||
MJC03416_2 | |||||||||
ES410604.1 | |||||||||
HBC16162_1 | |||||||||
TDC02902_1 | |||||||||
BF064305.1 | |||||||||
EX007830.1 | |||||||||
GR367571.1 | |||||||||
BG310637.1 | |||||||||
ASC04448_1 | |||||||||
JI212713.1 | |||||||||
MH06323 | |||||||||
JI221507.1 | |||||||||
GT737483.1 | |||||||||
MC04676 | |||||||||
JI475500.1 | |||||||||
HG03202 | |||||||||
GR17216 | |||||||||
FE910742.1 | |||||||||
AIC00120_1 | |||||||||
FE918756.1 | |||||||||
HGC06301_1 | |||||||||
CRC06479_1 | |||||||||
BI773129.1 | |||||||||
DN557765.1 | |||||||||
EX013978.1 | |||||||||
MHC00281_1 | |||||||||
ES741831.1 | |||||||||
EX010379.1 | |||||||||
EX910926.1 | |||||||||
ASC17437_1 | |||||||||
GR17581 | |||||||||
U47812.1 | |||||||||
Tcir_isotig07131 | |||||||||
BMC04073_1 | |||||||||
EX008115.1 | |||||||||
JI483999.1 | |||||||||
BI772921.1 | |||||||||
FE915542.1 | |||||||||
JK315350.1 | |||||||||
CBC00147_1 | |||||||||
JI225260.1 | |||||||||
EX556301.1 | |||||||||
Hbac_isotig00273 | |||||||||
JI466355.1 | |||||||||
GW408822.1 | |||||||||
PPC03295_1 | |||||||||
GPC00018_1 | |||||||||
HG11884 | |||||||||
MJ00669 | |||||||||
PPC03363_1 | |||||||||
MHC11560_1 | |||||||||
JK315949.1 | |||||||||
DAC00185_1 | |||||||||
JI211694.1 | |||||||||
JI257347.1 | |||||||||
PP01013 | |||||||||
Hbac_isotig02984 | |||||||||
HCC00822_1 | |||||||||
NB06582 | |||||||||
GR17215 | |||||||||
PT01563 | |||||||||
GW413506.1 | |||||||||
EH005161.1 | |||||||||
MI01736 | |||||||||
FE912735.1 | |||||||||
AS01408 | |||||||||
CR08988 | |||||||||
MIC01281_2 | |||||||||
MC04727 | |||||||||
OF00831 | |||||||||
BI773560.1 | |||||||||
GR18152 | |||||||||
BF599155.1 | |||||||||
OOC03051_1 | |||||||||
ES411893.1 | |||||||||
U47813.1 | |||||||||
EX912229.1 | |||||||||
MP01502 | |||||||||
NBC03598_1 | |||||||||
MH11001 | |||||||||
CR00411 | |||||||||
EH005296.1 | |||||||||
NB07160 | |||||||||
PVC02246_1 | |||||||||
CBC04860_1 | |||||||||
HGC00913_1 | |||||||||
DA00260 | |||||||||
FC817860.1 | |||||||||
JI217581.1 | |||||||||
GRC00236_1 | |||||||||
MC01137 | |||||||||
MJ00094 | |||||||||
EL888729.1 | |||||||||
AE01335 | |||||||||
EL888086.1 | |||||||||
NBC00066_1 | |||||||||
HG02046 | |||||||||
PPC12528_1 | |||||||||
GO251056.1 | |||||||||
GW411427.1 | |||||||||
JK314763.1 | |||||||||
JI213541.1 | |||||||||
LSC00823_1 | |||||||||
HBC20577_1 | |||||||||
Hbac_isotig00272 | |||||||||
MIC01281_1 | |||||||||
PSC02695_2 | |||||||||
MI02417 | |||||||||
HGC01931_1 | |||||||||
EV852614.1 | |||||||||
Tcol_isotig06027 | |||||||||
OVC07850_1 | |||||||||
FE910242.1 | |||||||||
BE720997.1 | |||||||||
FE919815.1 | |||||||||
MI02067 | |||||||||
GO253156.1 | |||||||||
GR11873 | |||||||||
HC02233 | |||||||||
BMC00215_1 | |||||||||
MHC07362_1 | |||||||||
MCC04717_1 | |||||||||
GP01773 | |||||||||
EX563076.1 | |||||||||
Acan_isotig16664 | |||||||||
MI04337 | |||||||||
DN191151.1 | |||||||||
NAC01344_1 | |||||||||
JO472858.1 | |||||||||
DVC03169_1 | |||||||||
FC812482.1 | |||||||||
ACC14614_1 | |||||||||
MAC01248_1 | |||||||||
Name_isotig02508 | |||||||||
ES412760.1 | |||||||||
ASC00145_1 | |||||||||
JI166556.1 | |||||||||
Associated_feature | WBsf647585 | ||||||||
WBsf977375 | |||||||||
WBsf977376 | |||||||||
WBsf1002255 | |||||||||
WBsf1002256 | |||||||||
WBsf1020992 | |||||||||
WBsf233011 | |||||||||
Experimental_info | RNAi_result | WBRNAi00076847 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00021430 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00058423 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00027819 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr984 | ||||||||
Expr985 | |||||||||
Expr1018223 | |||||||||
Expr1030544 | |||||||||
Expr1161844 | |||||||||
Expr2010671 | |||||||||
Expr2028911 | |||||||||
Drives_construct | WBCnstr00013833 | ||||||||
WBCnstr00037227 | |||||||||
Construct_product (2) | |||||||||
Microarray_results (23) | |||||||||
Expression_cluster (127) | |||||||||
Interaction (105) | |||||||||
Map_info | Map | V | Position | 7.54862 | Error | 0.006411 | |||
Positive | Positive_clone | Y15F7 | Author_evidence | Page AM | |||||
Y75B12B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
ZK526 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00002472 | ||||||||
WBPaper00003820 | |||||||||
WBPaper00018604 | |||||||||
WBPaper00026884 | |||||||||
WBPaper00032230 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00041771 | |||||||||
WBPaper00049828 | |||||||||
WBPaper00055090 | |||||||||
Remark | [Page AM] Is transpliced by SL-1. Isolated from mixed stage cDNA by A. P. Page using SL1, and known 3' seq from CEESH95F. (not mapped); Genbank U31077. | ||||||||
[JAH]Partial sequence identity 64% to human CYP gene, 66% to yeast CSBY. | |||||||||
CEESH95F,CEMSB85F,CEMSB85FB,CEMSB85R removed from sequence list and replaced by genomic_canonical Y75B12B.5. sdm 11/00 | |||||||||
PPIase or cyclophilin, EC 5.2.1.8 | |||||||||
This gene has been renamed with approval of the CGC (cyp-3->cyn-3) | Person_evidence | WBPerson466 | |||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |