WormBase Tree Display for Gene: WBGene00000879
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| WBGene00000879 | SMap | S_parent | Sequence | Y75B12B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyn-3 | Person_evidence | WBPerson466 | |||||
| Sequence_name | Y75B12B.5 | ||||||||
| Molecular_name | Y75B12B.5 | ||||||||
| Y75B12B.5.1 | |||||||||
| CE20374 | |||||||||
| Other_name | cyp-3 | Person_evidence | WBPerson466 | ||||||
| CELE_Y75B12B.5 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | cyn-3 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 Sep 2004 16:20:03 | WBPerson1971 | Name_change | CGC_name | cyp-3 -> cyn-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyn | ||||||||
| Allele (28) | |||||||||
| Legacy_information | [C.elegansII] NMK. Cyclophilin family, transspliced to SL1. YAC Y15F7. [TP] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOP5521 | ||||||||
| Ortholog (54) | |||||||||
| Paralog (18) | |||||||||
| Structured_description | Concise_description | cyn-3 encodes an abundantly expressed cyclophilin A isoform with peptidyl-prolyl isomerase activity in vitro, which closely resembles the prototypical CypA and is thus likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; cyn-3 is exclusively expressed in the single anterior excretory cell, and is dispensable for viability and gross morphology in mass RNAi screens. | Paper_evidence | WBPaper00002472 | |||||
| WBPaper00003820 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00026884 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 20 Mar 2007 00:00:00 | ||||||||
| Automated_description | Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in obsolete cell. Expressed in excretory system. Human ortholog(s) of this gene implicated in several diseases, including Bell's palsy; aggressive periodontitis; and gastrointestinal system cancer (multiple). Is an ortholog of human PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4947 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||
| DOID:9261 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
| DOID:1474 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
| DOID:526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
| DOID:12506 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9253) | ||||||
| Molecular_info | Corresponding_CDS | Y75B12B.5 | |||||||
| Corresponding_transcript | Y75B12B.5.1 | ||||||||
| Other_sequence | U31077 | ||||||||
| HSC01591_1 | |||||||||
| MC04529 | |||||||||
| MJC03416_1 | |||||||||
| ES410560.1 | |||||||||
| AM743421.1 | |||||||||
| RS07649 | |||||||||
| GRC00341_1 | |||||||||
| NB07599 | |||||||||
| GO252597.1 | |||||||||
| RSC02810_1 | |||||||||
| BF599212.1 | |||||||||
| BXC00733_1 | |||||||||
| MJ00021 | |||||||||
| AS03056 | |||||||||
| SS00170 | |||||||||
| Dviv_isotig16822 | |||||||||
| JI625639.1 | |||||||||
| EX014303.1 | |||||||||
| AS02793 | |||||||||
| AYC00194_2 | |||||||||
| JI463044.1 | |||||||||
| HCC00822_3 | |||||||||
| MJC00401_1 | |||||||||
| EG025472.1 | |||||||||
| MA01922 | |||||||||
| EH005629.1 | |||||||||
| PT02146 | |||||||||
| PE00078 | |||||||||
| ES412014.1 | |||||||||
| JI239671.1 | |||||||||
| CBC14468_1 | |||||||||
| HBC04166_1 | |||||||||
| AW600038.1 | |||||||||
| HC00013 | |||||||||
| HS00290 | |||||||||
| AI363650.1 | |||||||||
| FG581023.1 | |||||||||
| SRC05997_1 | |||||||||
| ACC28445_1 | |||||||||
| FE910012.1 | |||||||||
| GR11923 | |||||||||
| AI130079.1 | |||||||||
| BMC02578_1 | |||||||||
| Name_isotig06234 | |||||||||
| Dviv_isotig16823 | |||||||||
| EX911673.1 | |||||||||
| MCC02593_1 | |||||||||
| EX561321.1 | |||||||||
| OVC01099_1 | |||||||||
| PEC00274_1 | |||||||||
| HG03434 | |||||||||
| TS01412 | |||||||||
| MIC09181_1 | |||||||||
| BU086576.1 | |||||||||
| JI257349.1 | |||||||||
| AAC00250_1 | |||||||||
| Tcir_isotig13512 | |||||||||
| JI219938.1 | |||||||||
| HC00039 | |||||||||
| HCC00822_2 | |||||||||
| BQ804066.1 | |||||||||
| TS03678 | |||||||||
| CBC05026_1 | |||||||||
| MH02853 | |||||||||
| MJC03416_2 | |||||||||
| ES410604.1 | |||||||||
| HBC16162_1 | |||||||||
| TDC02902_1 | |||||||||
| BF064305.1 | |||||||||
| EX007830.1 | |||||||||
| GR367571.1 | |||||||||
| BG310637.1 | |||||||||
| ASC04448_1 | |||||||||
| JI212713.1 | |||||||||
| MH06323 | |||||||||
| JI221507.1 | |||||||||
| GT737483.1 | |||||||||
| MC04676 | |||||||||
| JI475500.1 | |||||||||
| HG03202 | |||||||||
| GR17216 | |||||||||
| FE910742.1 | |||||||||
| AIC00120_1 | |||||||||
| FE918756.1 | |||||||||
| HGC06301_1 | |||||||||
| CRC06479_1 | |||||||||
| BI773129.1 | |||||||||
| DN557765.1 | |||||||||
| EX013978.1 | |||||||||
| MHC00281_1 | |||||||||
| ES741831.1 | |||||||||
| EX010379.1 | |||||||||
| EX910926.1 | |||||||||
| ASC17437_1 | |||||||||
| GR17581 | |||||||||
| U47812.1 | |||||||||
| Tcir_isotig07131 | |||||||||
| BMC04073_1 | |||||||||
| EX008115.1 | |||||||||
| JI483999.1 | |||||||||
| BI772921.1 | |||||||||
| FE915542.1 | |||||||||
| JK315350.1 | |||||||||
| CBC00147_1 | |||||||||
| JI225260.1 | |||||||||
| EX556301.1 | |||||||||
| Hbac_isotig00273 | |||||||||
| JI466355.1 | |||||||||
| GW408822.1 | |||||||||
| PPC03295_1 | |||||||||
| GPC00018_1 | |||||||||
| HG11884 | |||||||||
| MJ00669 | |||||||||
| PPC03363_1 | |||||||||
| MHC11560_1 | |||||||||
| JK315949.1 | |||||||||
| DAC00185_1 | |||||||||
| JI211694.1 | |||||||||
| JI257347.1 | |||||||||
| PP01013 | |||||||||
| Hbac_isotig02984 | |||||||||
| HCC00822_1 | |||||||||
| NB06582 | |||||||||
| GR17215 | |||||||||
| PT01563 | |||||||||
| GW413506.1 | |||||||||
| EH005161.1 | |||||||||
| MI01736 | |||||||||
| FE912735.1 | |||||||||
| AS01408 | |||||||||
| CR08988 | |||||||||
| MIC01281_2 | |||||||||
| MC04727 | |||||||||
| OF00831 | |||||||||
| BI773560.1 | |||||||||
| GR18152 | |||||||||
| BF599155.1 | |||||||||
| OOC03051_1 | |||||||||
| ES411893.1 | |||||||||
| U47813.1 | |||||||||
| EX912229.1 | |||||||||
| MP01502 | |||||||||
| NBC03598_1 | |||||||||
| MH11001 | |||||||||
| CR00411 | |||||||||
| EH005296.1 | |||||||||
| NB07160 | |||||||||
| PVC02246_1 | |||||||||
| CBC04860_1 | |||||||||
| HGC00913_1 | |||||||||
| DA00260 | |||||||||
| FC817860.1 | |||||||||
| JI217581.1 | |||||||||
| GRC00236_1 | |||||||||
| MC01137 | |||||||||
| MJ00094 | |||||||||
| EL888729.1 | |||||||||
| AE01335 | |||||||||
| EL888086.1 | |||||||||
| NBC00066_1 | |||||||||
| HG02046 | |||||||||
| PPC12528_1 | |||||||||
| GO251056.1 | |||||||||
| GW411427.1 | |||||||||
| JK314763.1 | |||||||||
| JI213541.1 | |||||||||
| LSC00823_1 | |||||||||
| HBC20577_1 | |||||||||
| Hbac_isotig00272 | |||||||||
| MIC01281_1 | |||||||||
| PSC02695_2 | |||||||||
| MI02417 | |||||||||
| HGC01931_1 | |||||||||
| EV852614.1 | |||||||||
| Tcol_isotig06027 | |||||||||
| OVC07850_1 | |||||||||
| FE910242.1 | |||||||||
| BE720997.1 | |||||||||
| FE919815.1 | |||||||||
| MI02067 | |||||||||
| GO253156.1 | |||||||||
| GR11873 | |||||||||
| HC02233 | |||||||||
| BMC00215_1 | |||||||||
| MHC07362_1 | |||||||||
| MCC04717_1 | |||||||||
| GP01773 | |||||||||
| EX563076.1 | |||||||||
| Acan_isotig16664 | |||||||||
| MI04337 | |||||||||
| DN191151.1 | |||||||||
| NAC01344_1 | |||||||||
| JO472858.1 | |||||||||
| DVC03169_1 | |||||||||
| FC812482.1 | |||||||||
| ACC14614_1 | |||||||||
| MAC01248_1 | |||||||||
| Name_isotig02508 | |||||||||
| ES412760.1 | |||||||||
| ASC00145_1 | |||||||||
| JI166556.1 | |||||||||
| Associated_feature (7) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00076847 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00021430 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058423 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027819 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr984 | ||||||||
| Expr985 | |||||||||
| Expr1018223 | |||||||||
| Expr1030544 | |||||||||
| Expr1161844 | |||||||||
| Expr2010671 | |||||||||
| Expr2028911 | |||||||||
| Drives_construct | WBCnstr00013833 | ||||||||
| WBCnstr00037227 | |||||||||
| Construct_product | WBCnstr00013833 | ||||||||
| WBCnstr00037227 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (127) | |||||||||
| Interaction (105) | |||||||||
| Map_info | Map | V | Position | 7.54862 | Error | 0.006411 | |||
| Positive | Positive_clone | Y15F7 | Author_evidence | Page AM | |||||
| Y75B12B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| ZK526 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00002472 | ||||||||
| WBPaper00003820 | |||||||||
| WBPaper00018604 | |||||||||
| WBPaper00026884 | |||||||||
| WBPaper00032230 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041771 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | [Page AM] Is transpliced by SL-1. Isolated from mixed stage cDNA by A. P. Page using SL1, and known 3' seq from CEESH95F. (not mapped); Genbank U31077. | ||||||||
| [JAH]Partial sequence identity 64% to human CYP gene, 66% to yeast CSBY. | |||||||||
| CEESH95F,CEMSB85F,CEMSB85FB,CEMSB85R removed from sequence list and replaced by genomic_canonical Y75B12B.5. sdm 11/00 | |||||||||
| PPIase or cyclophilin, EC 5.2.1.8 | |||||||||
| This gene has been renamed with approval of the CGC (cyp-3->cyn-3) | Person_evidence | WBPerson466 | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
