WormBase Tree Display for Gene: WBGene00000224

WBGene00000224 Evidence: Author_evidence: Veljkovic E
      Verrey F
    From_analysis
  SMap: S_parent: Sequence: F26D10
  Identity: Version: 2
    Name: CGC_name: atgp-1
      Sequence_name: F26D10.9
      Molecular_name: F26D10.9a
        F26D10.9a.1
        CE32183
        F26D10.9b
        CE41226
        F26D10.9b.1
      Other_name: atg-1
        tag-95 CGC_data_submission
        CELE_F26D10.9 Accession_evidence: NDB BX284604
      Public_name: atgp-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change (2)
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: atgp
    Allele (151)
    Strain: WBStrain00035583
    RNASeq_FPKM (74)
    GO_annotation: 00102866
      00102867
      00107057
    Ortholog (61)
    Paralog: WBGene00000225 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00008220 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00011409 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: atgp-1 encodes a predicted amino acid transporter glycoprotein subunit; when co-expressed in Xenopus oocytes with the AAT-1 or AAT-3 catalytic subunit, ATGP-1 is not able to facilitate amino acid uptake, even though ATGP-1 is able to covalently associate with AAT-1 or AAT-3 in the Xenopus expression system; however, when co-expressed with AAT-9, ATGP-1 is able to enhance the activity of this catalytic subunit; when expressed alone or with AAT-3, ATGP-1 localizes to the cell surface; when co-expressed with AAT-1, ATGP-1 localizes intracellularly. Paper_evidence: WBPaper00006408
            WBPaper00024381
          Curator_confirmed: WBPerson1843
          Date_last_updated: 03 Mar 2006 00:00:00
      Automated_description: Predicted to enable hydrolase activity, acting on glycosyl bonds. Predicted to be involved in carbohydrate metabolic process. Located in plasma membrane. Human ortholog(s) of this gene implicated in cystinuria. Is an ortholog of human SLC3A1 (solute carrier family 3 member 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9266 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11025)
  Molecular_info: Corresponding_CDS: F26D10.9a
      F26D10.9b
    Corresponding_CDS_history: F26D10.9:wp88
    Corresponding_transcript: F26D10.9a.1
      F26D10.9b.1
    Other_sequence: HBC12976_1
      EX562478.1
      Oden_isotig02322
      FK806683.1
      EW743102.1
      CR06859
      Oden_isotig02328
      Oden_isotig02323
      HBC01768_1
      EY461432.1
      EY458989.1
      EW743848.1
      EX542887.1
      EY466183.1
      CRC01601_1
      HG01091
      Oden_isotig02326
      Oden_isotig02331
      EX542046.1
      FK803320.1
      EX536425.1
      FE907927.1
      Oden_isotig02327
      EW743185.1
      FK808143.1
      FK800685.1
      JI168250.1
      EX567215.1
      FC546388.1
      Oden_isotig02321
      AS02654
      Oden_isotig02330
      Oden_isotig02329
      ACC06955_1
      EY468954.1
      FC554713.1
      EW744377.1
      ES410557.1
      BG467561.1
      EX535744.1
      Oden_isotig02325
      Dviv_isotig16229
      Tcir_isotig06804
      SR05217
      FK802747.1
      BXC03849_1
      EY470638.1
      EX550065.1
      BQ381390.1
      EX547459.1
      Hbac_isotig01154
      EX535206.1
      ASC03649_1
      FK804225.1
      SRC06781_1
      MCC01907_1
      NAC00363_1
      CJC06526_1
      BG467861.1
      Oden_isotig02324
      HGC02259_1
      EX008468.1
      EX549855.1
      CR00842
      Acan_isotig07686
      EX541253.1
      ES739993.1
      FE915382.1
      ACC05835_1
      FC554755.1
      BU086550.1
      FC546357.1
      Name_isotig07735
      NAC00010_1
      CR00472
      EX545343.1
      CJC14907_1
      MC03247
      CBC17625_1
      EX534547.1
      EX547157.1
      EX541393.1
      Dviv_isotig16228
      EX557343.1
      EX009919.1
      Oden_isotig02320
      EX553649.1
      EX543077.1
      FF679228.1
      FK805148.1
      EX548104.1
      BG467924.1
      JO468010.1
    Associated_feature: WBsf646605
      WBsf660980
      WBsf660981
      WBsf717214
      WBsf981871
      WBsf229622
  Experimental_info: RNAi_result: WBRNAi00031434 Inferred_automatically: RNAi_primary
      WBRNAi00013927 Inferred_automatically: RNAi_primary
      WBRNAi00045611 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027197
      Expr1030141
      Expr1149524
      Expr2009498
      Expr2027735
    Drives_construct: WBCnstr00037993
    Construct_product: WBCnstr00037993
    Antibody: WBAntibody00000719
    Microarray_results (21)
    Expression_cluster (181)
    Interaction (33)
  Map_info: Map: IV Position: 16.2882 Error: 0.004481
    Positive: Positive_clone: F26D10 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4164
    Pseudo_map_position
  Reference: WBPaper00006408
    WBPaper00038491
    WBPaper00039044
    WBPaper00039099
    WBPaper00039519
    WBPaper00055090
    WBPaper00061547
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene