WormBase Tree Display for Gene: WBGene00044094

WBGene00044094 SMap: S_parent: Sequence: ZK265
  Identity: Version: 2
    Name: CGC_name: fitm-2 Person_evidence: WBPerson205
      Sequence_name: ZK265.9
      Molecular_name: ZK265.9
        ZK265.9.1
        CE38132
      Other_name: CELE_ZK265.9 Accession_evidence: NDB BX284601
      Public_name: fitm-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 27 Jan 2005 14:40:44 WBPerson1846 Event: Created
        2 09 Jan 2015 16:33:20 WBPerson2970 Name_change: CGC_name: fitm-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fitm
    Allele (23)
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00042950 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00066623 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00162103 Caenorhabditis brenneri From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00213854 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00227702 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g12185 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g348 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1978 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g3693 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g11213 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g1430 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g15564 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g6302 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g4314 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g10844 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      CSP40.g9859 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00531.g11914 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-fitm-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g17017 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00028.g1593 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_14329 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_000969 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g11986 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g11272 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10135900 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1546 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00216288 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00248553 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00090596 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00260383 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00294776 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000002727 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      SGD:S000003094 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      FB:FBgn0035586 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050306-28 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-050508-5 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:16135 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:33714 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:1915930 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:2444508 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
      RGD:1306911 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      RGD:1307696 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
    Structured_description: Concise_description: fitm-2 encodes an ortholog of FIT1 and FIT2, membrane proteins of the endoplasmic reticulum that both induce, and are required for, lipid droplet accumulation; more distantly, FITM-2 is orthologous to budding yeast Scs3p and Yft2p. Paper_evidence: WBPaper00031361
            WBPaper00031452
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 12 Jan 2015 00:00:00
      Automated_description: Predicted to enable acyl-coenzyme A diphosphatase activity. Involved in lipid droplet formation. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Siddiqi syndrome. Is an ortholog of human FITM2 (fat storage inducing transmembrane protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0081273 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16135)
  Molecular_info: Corresponding_CDS: ZK265.9
    Corresponding_transcript: ZK265.9.1
    Other_sequence (20)
    Associated_feature (4)
  Experimental_info: RNAi_result: WBRNAi00004921 Inferred_automatically: RNAi_primary
      WBRNAi00059318 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028705
      Expr1040185
      Expr1162751
      Expr2011794
      Expr2030032
    Drives_construct: WBCnstr00023764
    Construct_product: WBCnstr00023764
    Microarray_results (19)
    Expression_cluster (113)
    Interaction: WBInteraction000585770
  Map_info: Map: I Position: 2.70337
    Positive: Positive_clone: ZK265 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00048723
    WBPaper00049815
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene