WormBase Tree Display for Gene: WBGene00021311

WBGene00021311 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 2
    Name: CGC_name: thoc-5 Person_evidence: WBPerson1521
      Sequence_name: Y32H12A.2
      Molecular_name (6)
      Other_name: CELE_Y32H12A.2 Accession_evidence: NDB BX284603
      Public_name: thoc-5
    DB_info: Database: AceView gene 3G436
        WormQTL gene WBGene00021311
        WormFlux gene WBGene00021311
        NDB locus_tag CELE_Y32H12A.2
        Panther gene CAEEL|WormBase=WBGene00021311|UniProtKB=C2BR94
          family PTHR13375
        NCBI gene 175735
        RefSeq protein NM_001267997.3
            NM_001267998.4
        TREEFAM TREEFAM_ID TF314812
        TrEMBL UniProtAcc H2L0N5
            C2BR94
        UniProt_GCRP UniProtAcc C2BR94
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 02 May 2017 10:45:03 WBPerson2970 Name_change: CGC_name: thoc-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: thoc
    Allele (41)
    RNASeq_FPKM (74)
    GO_annotation: 00006811
      00006812
      00006813
      00006814
      00006815
      00006816
      00006817
    Contained_in_operon: CEOP3292
    Ortholog: WBGene00042734 Caenorhabditis briggsae From_analysis: OrthoMCL
            Inparanoid_8
            WormBase-Compara
      WBGene00121252 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00153370 Caenorhabditis brenneri From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00055706 Caenorhabditis remanei From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00226614 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5442 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g13100 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1079 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g9551 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g15216 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g14149 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g10336 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g664 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g29157 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g12297 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00080.g3683 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-Y32H12A.2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold628.g7428 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00448.g11501 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_13519 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_010520 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g04037 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g20253 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30116200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7696 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00215472 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00244578 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00300543 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0034939 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-030131-3789 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:19074 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1351333 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1304991 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: Y32H12A.2 encodes the C. elegans ortholog of mammalian THOC5, a subunit of the THO complex involved in mRNP biogenesis as part of transcription elongation, mRNA maturation, and export. Paper_evidence: WBPaper00041879
          Curator_confirmed: WBPerson1843
          Date_last_updated: 09 Jan 2013 00:00:00
      Automated_description: Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus and positive regulation of DNA-templated transcription, elongation. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in breast carcinoma. Is an ortholog of human THOC5 (THO complex subunit 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3459 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:19074)
  Molecular_info: Corresponding_CDS: Y32H12A.2a
      Y32H12A.2b
    Corresponding_CDS_history: Y32H12A.2:wp202
    Corresponding_transcript: Y32H12A.2a.1
      Y32H12A.2b.1
    Other_sequence (23)
    Associated_feature: WBsf651042
      WBsf666901
      WBsf226663
      WBsf226664
      WBsf226665
      WBsf226666
  Experimental_info: RNAi_result (13)
    Expr_pattern: Expr13875
      Expr1019175
      Expr1039290
      Expr1159336
      Expr2017392
      Expr2035531
    Drives_construct: WBCnstr00024587
    Construct_product: WBCnstr00024587
      WBCnstr00040172
    Regulate_expr_cluster: WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055103:thoc-5(wy822)_upregulated
    Microarray_results (29)
    Expression_cluster (114)
    Interaction (16)
  Map_info: Map: III Position: -1.80654
    Positive: Positive_clone: Y32H12A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00037145
    WBPaper00038491
    WBPaper00041069
    WBPaper00041879
    WBPaper00052341
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene