WormBase Tree Display for Gene: WBGene00020197

WBGene00020197 SMap: S_parent: Sequence: T03G11
  Identity: Version: 2
    Name: CGC_name: mans-3 Paper_evidence: WBPaper00041024
          Person_evidence: WBPerson2099
      Sequence_name: T03G11.4
      Molecular_name: T03G11.4
        T03G11.4.1
        CE29462
      Other_name: CELE_T03G11.4 Accession_evidence: NDB BX284606
      Public_name: mans-3
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 11 May 2012 16:05:19 WBPerson2970 Name_change: CGC_name: mans-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mans
    Allele (50)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00051724 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00035057 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00160968 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00134923 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00225785 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g3064 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g16755 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g19008 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g15585 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g21435 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g8338 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g21699 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g2874 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g19104 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00067.g3241 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_00067.g3242 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-mans-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold567.g4160 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01755.g22943 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_00554 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_024375 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03029 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g21019 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0244100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g19027 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239951 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00109650 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00265546 Strongyloides ratti From_analysis: WormBase-Compara
      SGD:S000003892 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0039634 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-070705-482 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-091116-34 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:6823 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:2684954 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1563595 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog: WBGene00008258 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008411 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013881 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00008148 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008646 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013919 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: mans-3 is an ortholog of human MAN1B1 (mannosidase, alpha1B, member 1); mans-3 has a calcium ion dependent mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ('ER-mannosidase'), based on enzymatic assay, with Man8GlcNAc2 (isomer B) as a final product. Paper_evidence: WBPaper00041024
          Person_evidence: WBPerson2099
          Curator_confirmed: WBPerson324
          Date_last_updated: 10 Feb 2016 00:00:00
      Automated_description: Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in Rafiq syndrome. Is an ortholog of human MAN1B1 (mannosidase alpha class 1B member 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0081097 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6823)
  Molecular_info: Corresponding_CDS: T03G11.4
    Corresponding_transcript: T03G11.4.1
    Other_sequence (15)
    Associated_feature: WBsf648079
      WBsf648080
      WBsf1005190
      WBsf235678
      WBsf235679
      WBsf235680
  Experimental_info: RNAi_result: WBRNAi00018090 Inferred_automatically: RNAi_primary
      WBRNAi00078164 Inferred_automatically: RNAi_primary
      WBRNAi00033496 Inferred_automatically: RNAi_primary
      WBRNAi00052304 Inferred_automatically: RNAi_primary
      WBRNAi00076638 Inferred_automatically: RNAi_primary
      WBRNAi00018091 Inferred_automatically: RNAi_primary
      WBRNAi00052305 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021217
      Expr1038787
      Expr1155940
      Expr2013371
      Expr2031603
    Drives_construct: WBCnstr00025305
    Construct_product: WBCnstr00025305
    Microarray_results (21)
    Expression_cluster (80)
    Interaction: WBInteraction000226781
      WBInteraction000279187
      WBInteraction000296522
      WBInteraction000349661
      WBInteraction000404106
      WBInteraction000466500
      WBInteraction000466501
      WBInteraction000469189
      WBInteraction000470607
  Map_info: Map: X Position: -6.11483
    Positive: Positive_clone: T03G11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00029024
    WBPaper00038491
    WBPaper00055090
    WBPaper00065080
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene