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WormBase Tree Display for Gene: WBGene00019869

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Name Class

WBGene00019869SMapS_parentSequenceR04E5
IdentityVersion2
NameCGC_namecnnm-2Person_evidenceWBPerson32343
WBPerson32344
Sequence_nameR04E5.2
Molecular_nameR04E5.2
R04E5.2.1
CE53658
Other_nameCELE_R04E5.2Accession_evidenceNDBBX284606
Public_namecnnm-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:02WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
204 Jan 2016 15:29:00WBPerson2970Name_changeCGC_namecnnm-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcnnm
Allele (78)
RNASeq_FPKM (74)
GO_annotation (13)
OrthologWBGene00086140Caenorhabditis remaneiFrom_analysisTreeFam
WBGene00159279Caenorhabditis brenneriFrom_analysisTreeFam
WBGene00035721Caenorhabditis briggsaeFrom_analysisOrthoMCL
OMA
Inparanoid_8
WormBase-Compara
WBGene00070607Caenorhabditis remaneiFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00156045Caenorhabditis brenneriFrom_analysisOMA
TreeFam
Inparanoid_8
WormBase-Compara
WBGene00124030Caenorhabditis japonicaFrom_analysisTreeFam
Inparanoid_8
WormBase-Compara
CBOVI.g13099Caenorhabditis bovisFrom_analysisWormBase-Compara
CSP21.g14758Caenorhabditis parvicaudaFrom_analysisWormBase-Compara
CSP26.g659Caenorhabditis zanzibariFrom_analysisWormBase-Compara
CSP28.g11712Caenorhabditis panamensisFrom_analysisWormBase-Compara
CSP29.g23566Caenorhabditis beceiFrom_analysisWormBase-Compara
CSP31.g24682Caenorhabditis uteleiaFrom_analysisWormBase-Compara
CSP32.g4785Caenorhabditis sulstoniFrom_analysisWormBase-Compara
CSP38.g100Caenorhabditis quiockensisFrom_analysisWormBase-Compara
CSP39.g19256Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP39.g19496Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP39.g25325Caenorhabditis waitukubuliFrom_analysisWormBase-Compara
CSP40.g1742Caenorhabditis tribulationisFrom_analysisWormBase-Compara
Cang_2012_03_13_00239.g7660Caenorhabditis angariaFrom_analysisWormBase-Compara
Cni-cnnm-2Caenorhabditis nigoniFrom_analysisWormBase-Compara
Csp11.Scaffold629.g10940Caenorhabditis tropicalisFrom_analysisWormBase-Compara
Csp5_scaffold_00049.g2538Caenorhabditis sinicaFrom_analysisWormBase-Compara
FL83_02097Caenorhabditis latensFrom_analysisWormBase-Compara
GCK72_025231Caenorhabditis remaneiFrom_analysisWormBase-Compara
Sp34_X0173000Caenorhabditis inopinataFrom_analysisWormBase-Compara
chrX_pilon.g19646Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00081163Caenorhabditis remaneiFrom_analysisWormBase-Compara
FB:FBgn0262124Drosophila melanogasterFrom_analysisOrthoFinder
Panther
PhylomeDB
ZFIN:ZDB-GENE-050208-36Danio rerioFrom_analysisOrthoFinder
Panther
PhylomeDB
ZFIN:ZDB-GENE-090311-26Danio rerioFrom_analysisOrthoFinder
Panther
PhylomeDB
HGNC:105Homo sapiensFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
HGNC:104Homo sapiensFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
HGNC:102Homo sapiensFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
HGNC:103Homo sapiensFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
MGI:1891366Mus musculusFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
MGI:2151055Mus musculusFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
MGI:2151054Mus musculusFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
MGI:2151060Mus musculusFrom_analysisOrthoFinder
OrthoInspector
Panther
PhylomeDB
RGD:1308162Rattus norvegicusFrom_analysisOrthoFinder
Panther
PhylomeDB
RGD:1307926Rattus norvegicusFrom_analysisOrthoFinder
Panther
PhylomeDB
RGD:1305571Rattus norvegicusFrom_analysisOrthoFinder
Panther
PhylomeDB
ParalogWBGene00007255Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00011260Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016343Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016879Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionR04E5.2 encodes a predicted transmembrane protein orthologous to humanACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2,C52D10.12, M02F4.3, and R13G10.4; by orthology with MAM3, R04E5.2 mayparticipate in metal homoeostasis; R04E5.2, MAM3, and ACDP1-ACDP4 belongto a family of proteins (sharing an ACD domain) from bacteria, yeast,plants, and metazoa; murine Acdp1 is a plasma membrane protein;bacterial proteins containing the ACD domain include CorC fromSalmonella typhimurium, which is involved in magnesium and cobaltefflux; R04E5.2 has no obvious function in RNAi assays.Paper_evidenceWBPaper00004651
WBPaper00005654
WBPaper00013242
WBPaper00013325
WBPaper00013365
WBPaper00013531
WBPaper00028771
Curator_confirmedWBPerson567
Date_last_updated09 Nov 2006 00:00:00
Automated_descriptionPredicted to enable transmembrane transporter activity. Involved in determination of adult lifespan and positive regulation of gonad development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Jalili syndrome and renal hypomagnesemia 6. Is an ortholog of several human genes including CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1); CNNM3 (cyclin and CBS domain divalent metal cation transport mediator 3); and CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060884Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:103)
EFO:MONDO:0014631Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:103)
DOID:0111404Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:105)
Molecular_infoCorresponding_CDSR04E5.2
Corresponding_CDS_historyR04E5.2:wp272
Corresponding_transcriptR04E5.2.1
Other_sequenceMIC02161_1
EL784675.1
EL784329.1
MI04241
MI01658
Associated_featureWBsf648382
WBsf1006254
WBsf1006255
WBsf1023471
WBsf1023472
WBsf1023473
WBsf236090
Experimental_infoRNAi_result (4)
Expr_patternExpr1014513
Expr1038618
Expr1154947
Expr2010278
Expr2028520
Drives_constructWBCnstr00025532
Construct_productWBCnstr00025532
Microarray_results (21)
Expression_cluster (131)
InteractionWBInteraction000237184
WBInteraction000411098
WBInteraction000465345
Map_infoMapXPosition0.410087
PositivePositive_cloneR04E5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00050045
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene