WormBase Tree Display for Gene: WBGene00018398

WBGene00018398 SMap: S_parent: Sequence: F43H9
  Identity: Version: 2
    Name: CGC_name: sptl-2 Person_evidence: WBPerson237
            WBPerson3098
      Sequence_name: F43H9.2
      Molecular_name: F43H9.2a
        F43H9.2a.1
        CE07246
        F43H9.2b
        CE27380
        F43H9.2b.1
        F43H9.2b.2
      Other_name: CELE_F43H9.2 Accession_evidence: NDB BX284605
      Public_name: sptl-2
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 06 May 2005 10:44:15 WBPerson2970 Name_change: CGC_name: sptl-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: sptl
    Allele (62)
    Strain: WBStrain00037282
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00052967 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00032511 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00153362 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00116181 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00121981 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00224335 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g1118 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g10102 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g8650 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g4346 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g9369 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g8156 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g6814 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g2001 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g9779 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g7583 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00199.g6837 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_12747.g23912 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-sptl-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold615.g6009 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00649.g13998 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_03671 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_018733 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g05254 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g5839 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50099200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g14880 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244026 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00255785 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00285517 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000002469 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0002524 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-041210-281 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050522-23 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080305-8 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11278 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:16253 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:108074 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2444678 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310030 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1305447 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00011932 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012007 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016020 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in ceramide biosynthetic process and sphingosine biosynthetic process. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Is an ortholog of human SPTLC2 (serine palmitoyltransferase long chain base subunit 2) and SPTLC3 (serine palmitoyltransferase long chain base subunit 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070157 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11278)
  Molecular_info: Corresponding_CDS: F43H9.2a
      F43H9.2b
    Corresponding_transcript (3)
    Other_sequence (62)
    Associated_feature: WBsf646978
      WBsf718342
      WBsf1000563
      WBsf1000564
      WBsf232045
      WBsf232046
  Experimental_info: RNAi_result: WBRNAi00023229 Inferred_automatically: RNAi_primary
      WBRNAi00024027 Inferred_automatically: RNAi_primary
      WBRNAi00047230 Inferred_automatically: RNAi_primary
      WBRNAi00032207 Inferred_automatically: RNAi_primary
      WBRNAi00023741 Inferred_automatically: RNAi_primary
      WBRNAi00047229 Inferred_automatically: RNAi_primary
      WBRNAi00023465 Inferred_automatically: RNAi_primary
      WBRNAi00014895 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014380
      Expr1037925
      Expr1151089
      Expr2016105
      Expr2034340
    Drives_construct: WBCnstr00026551
    Construct_product: WBCnstr00016266
      WBCnstr00026551
    Microarray_results (30)
    Expression_cluster (241)
    Interaction (106)
    WBProcess: WBbiopr:00000137
  Map_info: Map: V Position: 1.00219 Error: 0.000469
    Positive: Positive_clone: F43H9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026204
    WBPaper00038491
    WBPaper00040204
    WBPaper00042257
    WBPaper00055090
    WBPaper00056971
    WBPaper00061178
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene