Predicted to contribute to GTPase activator activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of TORC1 signaling; and positive regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol. Expressed in excretory cell; nervous system; spermatheca; and vulva. Used to study Birt-Hogg-Dube syndrome. Human ortholog(s) of this gene implicated in several diseases, including Birt-Hogg-Dube syndrome; primary spontaneous pneumothorax; and renal cell carcinoma. Is an ortholog of human FLCN (folliculin).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.