WormBase Tree Display for Gene: WBGene00012354

WBGene00012354 SMap: S_parent: Sequence: W09C5
  Identity: Version: 2
    Name: CGC_name: cox-4 Person_evidence: WBPerson117
            WBPerson7169
      Sequence_name: W09C5.8
      Molecular_name: W09C5.8
        W09C5.8.1
        CE20171
      Other_name: CELE_W09C5.8 Accession_evidence: NDB BX284601
      Public_name: cox-4
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 05 Sep 2017 13:25:30 WBPerson2970 Name_change: CGC_name: cox-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cox
    Allele (24)
    Strain: WBStrain00037231
      WBStrain00022511
      WBStrain00047268
    RNASeq_FPKM (74)
    GO_annotation: 00099906
      00099907
      00099908
      00099909
      00099910
      00099911
      00099912
      00099913
      00119507
      00119508
    Ortholog: WBGene00061173 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00038936 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00131982 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00141991 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00151737 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00226513 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g10451 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g6310 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g12545 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g8198 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g21257 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g5984 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g5407 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g1762 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g2365 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g7359 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00152.g5722 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-W09C5.8 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g20980 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_03374.g29983 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_19325 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_003597 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g06281 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g8402 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10012900 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g2769 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00248728 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00272012 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00274081 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00260838 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00293679 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001373 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Panther
      SGD:S000004997 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Panther
      FB:FBgn0032833 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0033020 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-030131-5175 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1775 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-130814-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:2265 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      HGNC:16232 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:88473 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2135755 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:68374 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:69422 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: W09C5.8 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit IV (COX IV); loss of W09C5.8 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. Paper_evidence: WBPaper00032427
          Curator_confirmed: WBPerson1843
          Date_last_updated: 08 Nov 2010 00:00:00
      Automated_description: Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070501 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2265)
  Molecular_info (4)
  Experimental_info: RNAi_result (21)
    Expr_pattern: Expr1028081
      Expr1035471
      Expr1158573
      Expr2006884
      Expr2025111
    Drives_construct: WBCnstr00029984
    Construct_product: WBCnstr00029984
    Microarray_results (23)
    Expression_cluster (110)
    Interaction (76)
  Map_info: Map: I Position: 21.6359
    Positive: Positive_clone: W09C5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene