WormBase Tree Display for Gene: WBGene00011906

WBGene00011906 SMap: S_parent: Sequence: T22A3
  Identity: Version: 2
    Name: CGC_name: hsp-12.1 Person_evidence: WBPerson36
      Sequence_name: T22A3.2
      Molecular_name: T22A3.2a
        T22A3.2a.1
        CE13914
        T22A3.2b
        CE40519
        T22A3.2b.1
      Other_name: CELE_T22A3.2 Accession_evidence: NDB BX284601
      Public_name: hsp-12.1
    DB_info: Database: WormQTL gene WBGene00011906
        WormFlux gene WBGene00011906
        NDB locus_tag CELE_T22A3.2
        Panther gene CAEEL|WormBase=WBGene00011906|UniProtKB=G5EE65
          family PTHR45640
        NCBI gene 188710
        RefSeq protein NM_001083144.2
            NM_001083145.4
        TrEMBL UniProtAcc G5EE65
            O01263
        UniProt_GCRP UniProtAcc G5EE65
        OMIM gene 123580
            123590
            602195
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 28 Jul 2004 13:52:33 WBPerson1971 Name_change: CGC_name: hsp-12.1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: hsp
    Allele (21)
    Strain: WBStrain00033275
    RNASeq_FPKM (74)
    GO_annotation: 00015479
      00015480
      00015481
      00015482
      00015483
      00015484
      00015485
    Ortholog: WBGene00059900 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00042794 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00207460 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00025335 Caenorhabditis briggsae From_analysis: WormBase-Compara
      WBGene00222456 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g10501 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g6767 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g14096 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g14785 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g2995 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g16127 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g5378 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g18662 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g23965 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g15146 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00682.g13405 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_I.g2091 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold547.g3539 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00385.g10521 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_05187 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002416 Caenorhabditis remanei From_analysis: WormBase-Compara
      Sp34_10213310 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g2083 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00262025 Strongyloides ratti From_analysis: WormBase-Compara
      FB:FBgn0032181 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
      ZFIN:ZDB-GENE-991119-2 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030326-4 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-040718-419 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-050417-260 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoInspector
            SonicParanoid
      ZFIN:ZDB-GENE-020508-1 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:2388 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:2389 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:5246 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoInspector
            SonicParanoid
      HGNC:5247 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      HGNC:26511 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:CRYAA2 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      MGI:88515 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoInspector
            Panther
            SonicParanoid
      MGI:88516 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoInspector
            Panther
            SonicParanoid
      MGI:96240 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoInspector
            SonicParanoid
      MGI:1916503 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            SonicParanoid
      MGI:2685325 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      RGD:2413 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoInspector
            Panther
            SonicParanoid
      RGD:61306 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoInspector
            SonicParanoid
      RGD:2414 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoInspector
            Panther
            SonicParanoid
      RGD:70914 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoInspector
            SonicParanoid
      RGD:621554 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoInspector
            Panther
            SonicParanoid
    Paralog (17)
    Structured_description: Concise_description: hsp-12.1 encodes a member of the small heat shock family of proteins. Paper_evidence: WBPaper00013029
          Curator_confirmed: WBPerson1843
          Date_last_updated: 02 Mar 2007 00:00:00
      Automated_description: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in striated muscle dense body. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease axonal type 2F; cataract (multiple); and myofibrillar myopathy (multiple). Is an ortholog of human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB6 (heat shock protein family B (small) member 6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (11)
  Molecular_info: Corresponding_CDS (2)
    Corresponding_transcript: T22A3.2a.1
      T22A3.2b.1
    Other_sequence (82)
    Associated_feature: WBsf655318
      WBsf985040
      WBsf220257
      WBsf220258
      WBsf220259
  Experimental_info: RNAi_result: WBRNAi00116981 Inferred_automatically: RNAi_primary
      WBRNAi00035777 Inferred_automatically: RNAi_primary
      WBRNAi00053771 Inferred_automatically: RNAi_primary
      WBRNAi00076696 Inferred_automatically: RNAi_primary
      WBRNAi00106376 Inferred_automatically: RNAi_primary
      WBRNAi00004252 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9395
      Expr15506
      Expr1021401
      Expr1035252
      Expr1157322
      Expr2012612
      Expr2030848
    Drives_construct: WBCnstr00030294
      WBCnstr00042197
    Construct_product: WBCnstr00013960
      WBCnstr00030294
      WBCnstr00042197
    Antibody: WBAntibody00003010
    Microarray_results (20)
    Expression_cluster (170)
    Interaction (48)
  Map_info: Map: I Position: 5.05599 Error: 6.2e-05
    Positive: Positive_clone: T22A3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene