WormBase Tree Display for Gene: WBGene00009918

WBGene00009918 SMap: S_parent: Sequence: F52A8
  Identity: Version: 2
    Name: CGC_name: gcsh-2 Person_evidence: WBPerson151
      Sequence_name: F52A8.5
      Molecular_name: F52A8.5
        F52A8.5.1
        CE05912
        F52A8.5.2
      Other_name: CELE_F52A8.5 Accession_evidence: NDB BX284601
      Public_name: gcsh-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Nov 2016 11:06:22 WBPerson2970 Name_change: CGC_name: gcsh-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gcsh
    Allele (16)
    Strain: WBStrain00049351
    RNASeq_FPKM (74)
    GO_annotation: 00068603
      00068604
      00068605
      00068606
      00068607
      00068608
      00068609
      00068610
      00117473
      00117474
    Ortholog: WBGene00032946 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00144262 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00150058 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00130076 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00067669 Caenorhabditis remanei From_analysis: TreeFam
            WormBase-Compara
      WBGene00175940 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      CBOVI.g9130 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g6378 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g10242 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g14923 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g2536 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g7820 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g8587 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g10798 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP32.g9863 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g5260 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g15891 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g9733 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g16772 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00040.g2208 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_I.g1792 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g17299 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_04230.g32417 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_15369 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_000138 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g10701 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_10088900 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1371 Caenorhabditis elegans From_analysis: WormBase-Compara
      FB:FBgn0027945 Drosophila melanogaster From_analysis: PhylomeDB
            EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      SGD:S000000042 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040718-319 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050320-18 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:4208 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1915383 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:619946 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1563099 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00008354 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: F52A8.5 is orthologous to the human gene GLYCINE CLEAVAGE SYSTEM PROTEIN H (GCSH; OMIM:238330), which when mutated leads to glycine encephalopathy. Paper_evidence: WBPaper00004424
          Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be located in mitochondrion. Predicted to be part of glycine cleavage complex. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and multiple mitochondrial dysfunctions syndrome. Is an ortholog of human GCSH (glycine cleavage system protein H). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9252 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4208)
      DOID:0070330 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4208)
  Molecular_info: Corresponding_CDS: F52A8.5
    Corresponding_transcript: F52A8.5.1
      F52A8.5.2
    Other_sequence (39)
    Associated_feature: WBsf649311
      WBsf649312
      WBsf984158
      WBsf1010073
      WBsf219747
      WBsf219748
      WBsf219749
      WBsf219750
  Experimental_info: RNAi_result (8)
    Expr_pattern: Expr1014754
      Expr1034318
      Expr1151738
      Expr2011974
      Expr2030211
    Drives_construct: WBCnstr00031817
    Construct_product: WBCnstr00031817
    Microarray_results (20)
    Expression_cluster (119)
    Interaction (45)
  Map_info: Positive: Positive_clone: F52A8 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 1.9367
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene