WormBase Tree Display for Gene: WBGene00003953

WBGene00003953 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F39H11
  Identity: Version: 1
    Name (5)
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pbs
    Allele (14)
    Strain: WBStrain00051314
      WBStrain00051922
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00060027 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00033305 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00164856 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00141994 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00125185 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00233938 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g9191 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g4879 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g10169 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g1775 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g703 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g8219 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g982 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g13856 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g27989 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g24267 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00805.g14252 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-pbs-7 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g20513 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00281.g8640 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_05051 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002554 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g06737 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g4880 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10246100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1652 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00237971 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00272488 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00261738 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00288645 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001946 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0250746 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050417-333 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:9541 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1098257 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:61877 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog (13)
    Structured_description: Concise_description: pbs-7 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-7 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-7 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-7 is required for normal movement and for embryonic, germline, and larval development. Paper_evidence: WBPaper00004402
            WBPaper00004540
            WBPaper00006395
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB4 (proteasome 20S subunit beta 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0060916 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9541)
  Molecular_info: Corresponding_CDS: F39H11.5
    Corresponding_transcript: F39H11.5.1
    Other_sequence (64)
    Associated_feature: WBsf649408
      WBsf219963
      WBsf219964
  Experimental_info: RNAi_result (29)
    Expr_pattern: Expr1022520
      Expr1031879
      Expr1150672
      Expr2014771
      Expr2033005
    Drives_construct: WBCnstr00035779
    Construct_product: WBCnstr00035779
    Microarray_results (21)
    Expression_cluster (147)
    Interaction (156)
  Map_info: Map: I Position: 3.01831 Error: 0.00013
    Positive: Positive_clone: F39H11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene