WormBase Tree Display for Gene: WBGene00003917
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WBGene00003917 | SMap | S_parent | Sequence | F58B6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | par-2 | Person_evidence | WBPerson314 | |||||
Sequence_name | F58B6.3 | ||||||||
Molecular_name (19) | |||||||||
Other_name | CELE_F58B6.3 | Accession_evidence | NDB | BX284603 | |||||
Public_name | par-2 | ||||||||
DB_info | Database | AceView | gene | 3C183 | |||||
WormQTL | gene | WBGene00003917 | |||||||
WormFlux | gene | WBGene00003917 | |||||||
NDB | locus_tag | CELE_F58B6.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00003917|UniProtKB=Q965F9 | |||||||
family | PTHR44080 | ||||||||
NCBI | gene | 175275 | |||||||
RefSeq | protein | NM_001420607.1 | |||||||
NM_001027459.7 | |||||||||
NM_001420609.1 | |||||||||
NM_001420606.1 | |||||||||
NM_001381725.1 | |||||||||
TrEMBL | UniProtAcc | A0A8S4SQT8 | |||||||
A0A8S4SL65 | |||||||||
A0A8S4SK97 | |||||||||
H1ZUX3 | |||||||||
Q965F9 | |||||||||
UniProt_GCRP | UniProtAcc | A0A8S4SQT8 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 02 Jan 2022 21:17:43 | WBPerson1983 | Event | Split_into | WBGene00306125 | ||||
Split_into | WBGene00306125 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | par | ||||||||
Allele (329) | |||||||||
Legacy_information | it46ts mat : homozygous hermaphrodites produce 90% (16x) to 99% (25x) arrested embryos escapers sterile; abnormal early cleavages defective P granule localization. ES3 (progeny). NA4 (it5ts : weaker phenotype e2030 : grandchildless). | ||||||||
See also e2030 | |||||||||
[C.elegansII] it46ts,mat : homozygous hermaphrodites produce 90% (16C) to 99% (25C) arrested embryos, escapers sterile; abnormal early cleavages, both spindles transverse at 2nd cleavage (failure of P1 rotation), defective P granule localization. ES3 (progeny). OA7: it5ts (weaker phenotype), e2030 (Mes, grandchildless),it87 (weak),jb2, etc. All ts; temp shift indicates not needed after 2nd cleavage. Cloned: encodes predicted novel protein. Antibody staining indicates specific asymmetric cortical localizations in early blastomeres. [Cheng et al. 1995; KK] | |||||||||
Strain (17) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (26) | |||||||||
Contained_in_operon | CEOP3056 | ||||||||
Ortholog | WBGene00065403 | Caenorhabditis remanei | From_analysis | OMA | |||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
WBGene00035482 | Caenorhabditis briggsae | From_analysis | Hillier-set | ||||||
OrthoMCL | |||||||||
OMA | |||||||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
WBGene00140516 | Caenorhabditis brenneri | From_analysis | OMA | ||||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
CBOVI.g5310 | Caenorhabditis bovis | From_analysis | WormBase-Compara | ||||||
CSP21.g14635 | Caenorhabditis parvicauda | From_analysis | WormBase-Compara | ||||||
CSP26.g3451 | Caenorhabditis zanzibari | From_analysis | WormBase-Compara | ||||||
CSP28.g12886 | Caenorhabditis panamensis | From_analysis | WormBase-Compara | ||||||
CSP29.g22609 | Caenorhabditis becei | From_analysis | WormBase-Compara | ||||||
CSP29.g22617 | Caenorhabditis becei | From_analysis | WormBase-Compara | ||||||
CSP31.g10959 | Caenorhabditis uteleia | From_analysis | WormBase-Compara | ||||||
CSP32.g10588 | Caenorhabditis sulstoni | From_analysis | WormBase-Compara | ||||||
CSP38.g7237 | Caenorhabditis quiockensis | From_analysis | WormBase-Compara | ||||||
CSP39.g7099 | Caenorhabditis waitukubuli | From_analysis | WormBase-Compara | ||||||
CSP40.g5292 | Caenorhabditis tribulationis | From_analysis | WormBase-Compara | ||||||
Cang_2012_03_13_00030.g1735 | Caenorhabditis angaria | From_analysis | WormBase-Compara | ||||||
Cnig_chr_III.g8482 | Caenorhabditis nigoni | From_analysis | WormBase-Compara | ||||||
Csp5_scaffold_01414.g20770 | Caenorhabditis sinica | From_analysis | WormBase-Compara | ||||||
FL83_16777 | Caenorhabditis latens | From_analysis | WormBase-Compara | ||||||
GCK72_011745 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||||
Sp34_30317000 | Caenorhabditis inopinata | From_analysis | WormBase-Compara | ||||||
chrIII_pilon.g6884 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
WBGene00125818 | Caenorhabditis japonica | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3. | Paper_evidence | WBPaper00005115 | |||||
WBPaper00005317 | |||||||||
WBPaper00005405 | |||||||||
WBPaper00005575 | |||||||||
WBPaper00005735 | |||||||||
WBPaper00005778 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables microtubule binding activity; phosphatidylinositol phosphate binding activity; and protein kinase binding activity. Involved in asymmetric cell division; asymmetric protein localization involved in cell fate determination; and establishment of mitotic spindle orientation. Located in P granule; posterior cell cortex; and protein-containing complex. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F58B6.3a | |||||||
F58B6.3b | |||||||||
F58B6.3c | |||||||||
F58B6.3d | |||||||||
F58B6.3e | |||||||||
Corresponding_CDS_history | F58B6.3:wp19 | ||||||||
F58B6.3a:wp229 | |||||||||
F58B6.3a:wp283 | |||||||||
F58B6.3b:wp150 | |||||||||
Corresponding_transcript | F58B6.3a.1 | ||||||||
F58B6.3b.1 | |||||||||
F58B6.3c.1 | |||||||||
F58B6.3d.1 | |||||||||
F58B6.3e.1 | |||||||||
F58B6.3e.2 | |||||||||
F58B6.3e.3 | |||||||||
F58B6.3e.4 | |||||||||
F58B6.3e.5 | |||||||||
Other_sequence | CR05646 | ||||||||
CRC02017_1 | |||||||||
MPC00003_1 | |||||||||
Associated_feature (14) | |||||||||
Experimental_info (9) | |||||||||
Map_info | Map | III | Position | -23.7021 | Error | 0.225136 | |||
Well_ordered | |||||||||
Positive | Positive_clone | F58B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Y11F11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
Mapping_data | 2_point | 2720 | |||||||
2721 | |||||||||
4699 | |||||||||
Multi_point (11) | |||||||||
Landmark_gene | |||||||||
Reference (312) | |||||||||
Method | Gene |