WormBase Tree Display for Gene: WBGene00003248
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| WBGene00003248 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F57B7 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | mig-17 | Person_evidence | WBPerson261 | |||||
| Sequence_name | F57B7.4 | ||||||||
| Molecular_name | F57B7.4 | ||||||||
| F57B7.4.1 | |||||||||
| CE31010 | |||||||||
| Other_name | CELE_F57B7.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | mig-17 | ||||||||
| DB_info | Database | AceView | gene | 5L929 | |||||
| WormQTL | gene | WBGene00003248 | |||||||
| WormFlux | gene | WBGene00003248 | |||||||
| NDB | locus_tag | CELE_F57B7.4 | |||||||
| NCBI | gene | 179575 | |||||||
| RefSeq | protein | NM_073500.8 | |||||||
| KEGG | KEGG_id | 3.4.24.- | |||||||
| NemaPath | KEGG_id | 3.4.24.- | |||||||
| SwissProt | UniProtAcc | Q20930 | |||||||
| UniProt_GCRP | UniProtAcc | Q20930 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mig | ||||||||
| Allele (38) | |||||||||
| Legacy_information | [Nishiwaki K ] DTC migration abnormal | ||||||||
| Strain | WBStrain00028694 | ||||||||
| WBStrain00028701 | |||||||||
| WBStrain00050676 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (40) | |||||||||
| Ortholog | WBGene00041601 | Caenorhabditis briggsae | From_analysis | Hillier-set | |||||
| OrthoMCL | |||||||||
| OMA | |||||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00139551 | Caenorhabditis brenneri | From_analysis | OMA | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00064749 | Caenorhabditis remanei | From_analysis | OMA | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00116002 | Pristionchus pacificus | From_analysis | OMA | ||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00120431 | Caenorhabditis japonica | From_analysis | Inparanoid_8 | ||||||
| WormBase-Compara | |||||||||
| WBGene00224771 | Brugia malayi | From_analysis | WormBase-Compara | ||||||
| CBOVI.g852 | Caenorhabditis bovis | From_analysis | WormBase-Compara | ||||||
| CSP21.g11554 | Caenorhabditis parvicauda | From_analysis | WormBase-Compara | ||||||
| CSP26.g11096 | Caenorhabditis zanzibari | From_analysis | WormBase-Compara | ||||||
| CSP28.g15490 | Caenorhabditis panamensis | From_analysis | WormBase-Compara | ||||||
| CSP29.g10320 | Caenorhabditis becei | From_analysis | WormBase-Compara | ||||||
| CSP32.g7124 | Caenorhabditis sulstoni | From_analysis | WormBase-Compara | ||||||
| CSP38.g19303 | Caenorhabditis quiockensis | From_analysis | WormBase-Compara | ||||||
| CSP39.g29197 | Caenorhabditis waitukubuli | From_analysis | WormBase-Compara | ||||||
| CSP40.g14488 | Caenorhabditis tribulationis | From_analysis | WormBase-Compara | ||||||
| Cang_2012_03_13_00421.g10634 | Caenorhabditis angaria | From_analysis | WormBase-Compara | ||||||
| Cni-mig-17 | Caenorhabditis nigoni | From_analysis | WormBase-Compara | ||||||
| Csp11.Scaffold629.g12676 | Caenorhabditis tropicalis | From_analysis | WormBase-Compara | ||||||
| Csp5_scaffold_03968.g31730 | Caenorhabditis sinica | From_analysis | WormBase-Compara | ||||||
| FL83_16739 | Caenorhabditis latens | From_analysis | WormBase-Compara | ||||||
| GCK72_016744 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||||
| Sp34_50323200 | Caenorhabditis inopinata | From_analysis | WormBase-Compara | ||||||
| chrV_pilon.g15775 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00243427 | Onchocerca volvulus | From_analysis | WormBase-Compara | ||||||
| WBGene00265079 | Strongyloides ratti | From_analysis | WormBase-Compara | ||||||
| FB:FBgn0034903 | Drosophila melanogaster | From_analysis | OrthoInspector | ||||||
| SonicParanoid | |||||||||
| Paralog (7) | |||||||||
| Structured_description | Concise_description | mig-17 encodes a secreted metalloprotease that is a member of the ADAM (A Disintegrin And Metalloprotease) protein family; MIG-17 activity is required for proper migration of gonadal leader cells, namely the hermaphrodite distal tip cells (DTCs) and the male linker cell (MLC); a MIG-17::GFP translational fusion protein is first detected in late embryos with expression continuing through adulthood; expression is initially seen on the pseudocoelomic face of body wall muscles and then on the surface of the gonad, when the DTCs migrate on the lateral hypodermis towards the dorsal muscles; proper MIG-17 localization and glycosylation requires activity of MIG-23, a membrane-bound nucleoside diphosphatase, as well as activity of COGC-3 and COGC-1, two members of the conserved oligomeric Golgi complex; expression studies with MIG-17 deletion derivatives indicate that MIG-17 is expressed by the body wall muscles and then localizes to the DTCs where its activity is sufficient for guiding DTC migration. | Paper_evidence | WBPaper00004167 | |||||
| WBPaper00006309 | |||||||||
| WBPaper00026979 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 14 May 2007 00:00:00 | ||||||||
| Automated_description | Enables metallopeptidase activity. Involved in several processes, including gonad morphogenesis; protein processing; and regulation of distal tip cell migration. Located in basement membrane and extracellular space. Expressed in several structures, including body wall musculature; gonad; head; intestine; and ventral nerve cord. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F57B7.4 | |||||||
| Corresponding_CDS_history | F57B7.4:wp51 | ||||||||
| F57B7.4:wp80 | |||||||||
| Corresponding_transcript | F57B7.4.1 | ||||||||
| Other_sequence | AB044562 | ||||||||
| CBC08395_1 | |||||||||
| Associated_feature | WBsf647263 | ||||||||
| WBsf661722 | |||||||||
| WBsf1001353 | |||||||||
| WBsf1001354 | |||||||||
| WBsf1020450 | |||||||||
| WBsf232506 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00015876 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00089090 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110308 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048830 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000262 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (14) | |||||||||
| Drives_construct | WBCnstr00010039 | ||||||||
| WBCnstr00010040 | |||||||||
| WBCnstr00012154 | |||||||||
| WBCnstr00012352 | |||||||||
| WBCnstr00018816 | |||||||||
| WBCnstr00036162 | |||||||||
| WBCnstr00041881 | |||||||||
| Construct_product | WBCnstr00010039 | ||||||||
| WBCnstr00012154 | |||||||||
| WBCnstr00018816 | |||||||||
| WBCnstr00019731 | |||||||||
| WBCnstr00036162 | |||||||||
| Antibody | WBAntibody00001254 | ||||||||
| WBAntibody00001441 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (131) | |||||||||
| Interaction (24) | |||||||||
| Map_info | Map | V | Position | 3.10659 | Error | 0.003887 | |||
| Positive | Positive_clone | F57B7 | Person_evidence | WBPerson449 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Mapping_data | Multi_point | 4255 | |||||||
| 4490 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (55) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
