WormBase Tree Display for Gene: WBGene00000964

WBGene00000964 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C47E12
  Identity: Version: 1
    Name: CGC_name: dhp-2 Person_evidence: WBPerson211
      Sequence_name: C47E12.8
      Molecular_name: C47E12.8
        C47E12.8.1
        CE05452
      Other_name: CeCRMP/DHP-2 Accession_evidence: EMBL AB040993
        CELE_C47E12.8 Accession_evidence: NDB BX284604
      Public_name: dhp-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dhp
    Allele (39)
    Legacy_information: common ancestor of CRMP and dihydropyrimidinase [Takemoto et al via email13]
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00065614 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00026309 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00040591 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00073676 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00151560 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00097130 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00126622 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00194750 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      CBOVI.g8593 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g2027 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g19332 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g2599 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g22138 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g13672 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g17194 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP39.g10928 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g2220 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g13049 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00022.g1365 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_03957.g18504 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_IV.g14360 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold585.g4826 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01076.g18187 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_20949 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014410 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g08666 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g6911 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40254100 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11463 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00266967 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00287291 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0023023 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030131-3136 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-050720-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-050720-4 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-050720-3 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-031105-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-050720-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-100914-5 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-070508-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:2365 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:3013 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:3014 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:3015 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:3016 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      HGNC:20637 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      MGI:107793 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
      MGI:1349763 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1349762 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1349764 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoInspector
            Panther
      MGI:1928679 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1929772 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
      RGD:2407 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      RGD:2517 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      RGD:2409 Rattus norvegicus From_analysis: Hieranoid
            OrthoInspector
            Panther
      RGD:2410 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      RGD:68376 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      RGD:620467 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoInspector
            Panther
    Paralog: WBGene00000963 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006769 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748). Paper_evidence: WBPaper00004637
          Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in pyrimidine nucleobase catabolic process. Located in cytoplasm. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Is an ortholog of human DPYS (dihydropyrimidinase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (3)
  Molecular_info: Corresponding_CDS: C47E12.8
    Corresponding_transcript: C47E12.8.1
    Other_sequence (50)
    Associated_feature: WBsf646270
      WBsf997529
      WBsf997530
      WBsf1018033
      WBsf228909
  Experimental_info: RNAi_result: WBRNAi00042682 Inferred_automatically: RNAi_primary
      WBRNAi00089011 Inferred_automatically: RNAi_primary
      WBRNAi00012077 Inferred_automatically: RNAi_primary
      WBRNAi00029914 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr835
      Expr836
      Expr1013617
      Expr1030599
      Expr1146671
      Expr2010891
      Expr2029130
    Drives_construct: WBCnstr00013281
      WBCnstr00037174
    Construct_product: WBCnstr00013281
      WBCnstr00037174
    Microarray_results (21)
    Expression_cluster (131)
    Interaction (12)
  Map_info: Map: IV Position: 4.4581 Error: 0.000963
    Positive: Positive_clone: C47E12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004552
    WBPaper00010035
    WBPaper00023701
    WBPaper00033099
    WBPaper00038491
    WBPaper00055090
    WBPaper00065140
    WBPaper00065331
  Remark: Sequence connection from [Kimura H]
    Synonyms : ULIP-A, CeCRMP/DHP-2
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene