WormBase Tree Display for Gene: WBGene00000093

WBGene00000093 SMap: S_parent: Sequence: Y62E10A
  Identity: Version: 1
    Name: CGC_name: agt-1
      Sequence_name: Y62E10A.5
      Molecular_name (6)
      Other_name: cAGT-1
        CELE_Y62E10A.5 Accession_evidence: NDB BX284604
      Public_name: agt-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: agt
    Allele (27)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Contained_in_operon: CEOP4542
    Ortholog: WBGene00062761 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00024971 Caenorhabditis briggsae From_analysis: OrthoMCL
            Inparanoid_8
            WormBase-Compara
      WBGene00139293 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00083557 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00074741 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00126056 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      CBOVI.g8737 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g13687 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g13864 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7000 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g5268 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g14436 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g906 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g4372 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g2402 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_06793.g20487 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_13362.g24193 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-agt-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold589.g5042 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00422.g11137 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_16018 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014536 Caenorhabditis remanei From_analysis: WormBase-Compara
      Sp34_40137910 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12283 Caenorhabditis elegans From_analysis: WormBase-Compara
      SGD:S000002359 Saccharomyces cerevisiae From_analysis: OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0024912 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-120614-1 Danio rerio From_analysis: Hieranoid
            OrthoInspector
            SonicParanoid
      HGNC:7059 Homo sapiens From_analysis: Hieranoid
            OrthoInspector
            SonicParanoid
      MGI:96977 Mus musculus From_analysis: Hieranoid
            OrthoInspector
      RGD:3087 Rattus norvegicus From_analysis: Hieranoid
            OrthoInspector
    Structured_description: Concise_description: agt-1 encodes an ortholog of the DNA repair enzyme O6-Alkylguanine DNA-alkyltransferase (AGT). Paper_evidence: WBPaper00004946
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables damaged DNA binding activity and transferase activity, transferring alkyl or aryl (other than methyl) groups. Involved in DNA dealkylation involved in DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); and high grade glioma (multiple). Is an ortholog of human MGMT (O-6-methylguanine-DNA methyltransferase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (13)
  Molecular_info: Corresponding_CDS: Y62E10A.5a
      Y62E10A.5b
    Corresponding_CDS_history: Y62E10A.5:wp140
    Corresponding_transcript: Y62E10A.5a.1
      Y62E10A.5b.1
    Other_sequence: CBC07082_1
    Associated_feature: WBsf231118
      WBsf231119
      WBsf231120
  Experimental_info: RNAi_result: WBRNAi00057853 Inferred_automatically: RNAi_primary
      WBRNAi00070719 Inferred_automatically: RNAi_primary
      WBRNAi00037674 Inferred_automatically: RNAi_primary
      WBRNAi00037675 Inferred_automatically: RNAi_primary
      WBRNAi00070720 Inferred_automatically: RNAi_primary
      WBRNAi00061945 Inferred_automatically: RNAi_primary
      WBRNAi00021216 Inferred_automatically: RNAi_primary
      WBRNAi00021217 Inferred_automatically: RNAi_primary
      WBRNAi00110764 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021901
      Expr1161287
      Expr2009265
      Expr2027502
    Drives_construct: WBCnstr00037740
    Construct_product: WBCnstr00037740
    Microarray_results (24)
    Expression_cluster (93)
    Interaction: WBInteraction000007965
      WBInteraction000045813
      WBInteraction000187174
      WBInteraction000192098
      WBInteraction000359067
      WBInteraction000435725
      WBInteraction000464204
  Map_info: Map: IV Position: 8.65316 Error: 0.025666
    Positive: Positive_clone: Y62E10A Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004946
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene