WormBase Tree Display for Gene: WBGene00021043

WBGene00021043 SMap: S_parent: Sequence: W05G11
  Identity: Version: 2
    Name: CGC_name: pck-1 Person_evidence: WBPerson2192
      Sequence_name: W05G11.6
      Molecular_name: W05G11.6
        W05G11.6.1
        CE19610
      Other_name: CELE_W05G11.6 Accession_evidence: NDB BX284603
      Public_name: pck-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 17 Feb 2012 16:57:01 WBPerson2970 Name_change: CGC_name: pck-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pck
    Allele (218)
    Strain: WBStrain00032381
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog: WBGene00065345 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00023849 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00030101 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00141689 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00092128 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00075791 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00138645 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00226459 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5586 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g28 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g11969 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g12979 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g22409 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g20940 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12042 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g21004 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g1167 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g6907 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00280.g8404 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_04080.g18591 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_17500.g25713 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_27523.g27543 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_III.g8602 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g16730 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01769.g23024 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_18615 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_011815 Caenorhabditis remanei From_analysis: WormBase-Compara
      Sp34_30318400 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g6697 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244846 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00288441 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0034356 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0003067 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030909-11 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040426-2266 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:8724 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:8725 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:97501 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1860456 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1311112 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:3267 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog: WBGene00011232 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00019151 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: pck-1 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of W05G11.6 are predicted to function in gluconeogenesis. Curator_confirmed: WBPerson1843
          Date_last_updated: 27 Jul 2012 00:00:00
      Automated_description: Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Located in cytosol and striated muscle dense body. Expressed in several structures, including body wall musculature; preanal ganglion; somatic nervous system; tail ganglion; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8724)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8724)
  Molecular_info: Corresponding_CDS: W05G11.6
    Corresponding_CDS_history: W05G11.6b:wp275
      W05G11.6d:wp275
    Corresponding_transcript: W05G11.6.1
    Other_sequence (167)
    Associated_feature (15)
  Experimental_info: RNAi_result (13)
    Expr_pattern: Expr9397
      Expr15024
      Expr15026
      Expr1024494
      Expr1039172
      Expr1158379
      Expr2014778
      Expr2033012
    Drives_construct: WBCnstr00041522
      WBCnstr00041875
      WBCnstr00041876
    Construct_product: WBCnstr00013962
      WBCnstr00041876
      WBCnstr00042950
      WBCnstr00042951
    Microarray_results (39)
    Expression_cluster (317)
    Interaction (47)
  Map_info: Map: III Position: -27.1341
    Positive: Positive_clone: W05G11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026800
    WBPaper00027145
    WBPaper00029292
    WBPaper00033086
    WBPaper00038444
    WBPaper00038491
    WBPaper00041315
    WBPaper00053236
    WBPaper00055090
    WBPaper00057505
    WBPaper00058434
    WBPaper00059520
    WBPaper00060127
    WBPaper00061616
    WBPaper00062625
    WBPaper00064602
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene