WormBase Tree Display for Gene: WBGene00018734
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WBGene00018734 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | Sequence_name | F53A10.2 | |||||||
Molecular_name | F53A10.2a | ||||||||
F53A10.2a.1 | |||||||||
CE24996 | |||||||||
F53A10.2b | |||||||||
CE32671 | |||||||||
F53A10.2c | |||||||||
CE37020 | |||||||||
F53A10.2d | |||||||||
CE51450 | |||||||||
F53A10.2e | |||||||||
CE51476 | |||||||||
F53A10.2f | |||||||||
CE20823 | |||||||||
F53A10.2b.1 | |||||||||
F53A10.2b.2 | |||||||||
F53A10.2b.3 | |||||||||
F53A10.2b.4 | |||||||||
F53A10.2b.5 | |||||||||
F53A10.2c.1 | |||||||||
F53A10.2d.1 | |||||||||
F53A10.2e.1 | |||||||||
F53A10.2f.1 | |||||||||
Other_name | CELE_F53A10.2 | Accession_evidence | NDB | BX284602 | |||||
Public_name | F53A10.2 | ||||||||
DB_info | Database | AceView | gene | 2B519 | |||||
WormQTL | gene | WBGene00018734 | |||||||
WormFlux | gene | WBGene00018734 | |||||||
NDB | locus_tag | CELE_F53A10.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00018734|UniProtKB=H2L055 | |||||||
family | PTHR15711 | ||||||||
NCBI | gene | 173502 | |||||||
RefSeq | protein | NM_001322703.3 | |||||||
NM_001322701.3 | |||||||||
NM_001393000.1 | |||||||||
NM_001393001.1 | |||||||||
NM_001322702.3 | |||||||||
NM_001027019.3 | |||||||||
TrEMBL | UniProtAcc | A0A131MBF2 | |||||||
H2L055 | |||||||||
A0A131MCP2 | |||||||||
A0A131MBM3 | |||||||||
Q8IA84 | |||||||||
Q965M4 | |||||||||
UniProt_GCRP | UniProtAcc | H2L055 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 29 Nov 2004 17:10:33 | WBPerson2970 | Event | Acquires_merge | WBGene00018733 | ||||
Acquires_merge | WBGene00018733 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Allele (847) | |||||||||
Strain | WBStrain00055198 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (8) | |||||||||
Ortholog (41) | |||||||||
Paralog | WBGene00012100 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | F53A10.2 encodes a Rap1GAP homolog; a region of F53A10.2 encompassing one GoLoco motif specifically binds GOA-1 in yeast two-hybrid assays, and also binds itself; F53A10.2 is expressed in hypodermal seam cells, various neurons, and intestinal cells; F53A10.2 has no obvious function or phenotype in RNAi assays, whether in a normal background or in goa-1(-) or goa-1(gf) mutant backgrounds. | Paper_evidence | WBPaper00006194 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytoplasm. Expressed in intestine; neurons; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; endocrine gland cancer (multiple); and myelodysplastic syndrome. Is an ortholog of human RAP1GAP (RAP1 GTPase activating protein) and RAP1GAP2 (RAP1 GTPase activating protein 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:3969 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||
DOID:3312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
DOID:0050908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
DOID:1909 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
DOID:1312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9858) | ||||||
Molecular_info | Corresponding_CDS | F53A10.2a | |||||||
F53A10.2b | |||||||||
F53A10.2c | |||||||||
F53A10.2d | |||||||||
F53A10.2e | |||||||||
F53A10.2f | |||||||||
Corresponding_transcript | F53A10.2a.1 | ||||||||
F53A10.2b.1 | |||||||||
F53A10.2b.2 | |||||||||
F53A10.2b.3 | |||||||||
F53A10.2b.4 | |||||||||
F53A10.2b.5 | |||||||||
F53A10.2c.1 | |||||||||
F53A10.2d.1 | |||||||||
F53A10.2e.1 | |||||||||
F53A10.2f.1 | |||||||||
Other_sequence (48) | |||||||||
Associated_feature (40) | |||||||||
Experimental_info | RNAi_result | WBRNAi00032647 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00063378 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015207 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00063366 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00020851 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00032648 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048037 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015447 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048036 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048038 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (6) | |||||||||
Drives_construct | WBCnstr00010936 | ||||||||
Construct_product | WBCnstr00010936 | ||||||||
Microarray_results (40) | |||||||||
Expression_cluster (108) | |||||||||
Interaction (40) | |||||||||
Map_info | Positive | Positive_clone | F53A10 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Interpolated_map_position | II | -15.5618 | |||||||
Reference | WBPaper00036647 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
Method | Gene |