WormBase Tree Display for Gene: WBGene00019993
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WBGene00019993 | SMap | S_parent | Sequence | R10A10 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | rbx-2 | |||||||
Sequence_name | R10A10.2 | ||||||||
Molecular_name | R10A10.2 | ||||||||
R10A10.2.1 | |||||||||
CE12670 | |||||||||
Other_name | CELE_R10A10.2 | Accession_evidence | NDB | BX284601 | |||||
Public_name | rbx-2 | ||||||||
DB_info | Database | AceView | gene | 1G996 | |||||
WormQTL | gene | WBGene00019993 | |||||||
WormFlux | gene | WBGene00019993 | |||||||
NDB | locus_tag | CELE_R10A10.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00019993|UniProtKB=P91404 | |||||||
family | PTHR11210 | ||||||||
NCBI | gene | 172344 | |||||||
RefSeq | protein | NM_059448.7 | |||||||
TREEFAM | TREEFAM_ID | TF351049 | |||||||
TrEMBL | UniProtAcc | P91404 | |||||||
UniProt_GCRP | UniProtAcc | P91404 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 15 Nov 2004 10:37:27 | WBPerson2970 | Name_change | CGC_name | rbx-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rbx | ||||||||
Allele (12) | |||||||||
Strain | WBStrain00032118 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00050896 | ||||||||
00050897 | |||||||||
00050898 | |||||||||
00050899 | |||||||||
00050900 | |||||||||
00050901 | |||||||||
00050902 | |||||||||
00124718 | |||||||||
Ortholog (31) | |||||||||
Paralog | WBGene00000145 | Caenorhabditis elegans | From_analysis (2) | ||||||
WBGene00004320 | Caenorhabditis elegans | From_analysis (2) | |||||||
Structured_description | Concise_description | The R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34. | Paper_evidence | WBPaper00012757 | |||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable cullin family protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of Cul5-RING ubiquitin ligase complex. Is an ortholog of human RNF7 (ring finger protein 7). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | R10A10.2 | |||||||
Corresponding_transcript | R10A10.2.1 | ||||||||
Other_sequence (21) | |||||||||
Associated_feature | WBsf649235 | ||||||||
WBsf983934 | |||||||||
WBsf983935 | |||||||||
WBsf1009956 | |||||||||
WBsf219580 | |||||||||
WBsf219581 | |||||||||
Experimental_info | RNAi_result (20) | ||||||||
Expr_pattern | Expr1015327 | ||||||||
Expr1038681 | |||||||||
Expr1155350 | |||||||||
Expr2015277 | |||||||||
Expr2033511 | |||||||||
Drives_construct | WBCnstr00025444 | ||||||||
Construct_product | WBCnstr00025444 | ||||||||
Microarray_results | SMD_R10A10.2 | ||||||||
173016_s_at | |||||||||
190241_at | |||||||||
A_12_P101692 | |||||||||
Aff_R10A10.2 | |||||||||
GPL13394_WBGene00019993 | |||||||||
GPL13914_R10A10.2 | |||||||||
GPL14144_R10A10.2_199-258_0.893_14_C | |||||||||
GPL14144_R10A10.2_242-301_0.961_1_A | |||||||||
GPL14144_R10A10.2_63-122_0.933_5_B | |||||||||
GPL19516_CGZ0031680 | |||||||||
GPL21109_R10A10.2 | |||||||||
GPL3518_CE12670 | |||||||||
GPL8304_CE_WBGene00019993_A | |||||||||
GPL8673_R10A10_2P00190 | |||||||||
GPL8673_R10A10_2P00241 | |||||||||
GPL8673_R10A10_2P00252 | |||||||||
GPL9450_R10A10.2 | |||||||||
cea2.p.15539 | |||||||||
Expression_cluster (75) | |||||||||
Interaction (36) | |||||||||
Map_info | Map | I | Position | 1.07719 | Error | 0.002046 | |||
Positive | Positive_clone | R10A10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00027315 | ||||||||
WBPaper00029151 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00052012 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00064339 | |||||||||
WBPaper00064898 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |