WormBase Tree Display for Gene: WBGene00019869
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WBGene00019869 | SMap | S_parent | Sequence | R04E5 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cnnm-2 | Person_evidence | WBPerson32343 | |||||
WBPerson32344 | |||||||||
Sequence_name | R04E5.2 | ||||||||
Molecular_name | R04E5.2 | ||||||||
R04E5.2.1 | |||||||||
CE53658 | |||||||||
Other_name | CELE_R04E5.2 | Accession_evidence | NDB | BX284606 | |||||
Public_name | cnnm-2 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 04 Jan 2016 15:29:00 | WBPerson2970 | Name_change | CGC_name | cnnm-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cnnm | ||||||||
Allele (78) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (41) | |||||||||
Paralog | WBGene00007255 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00011260 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00016343 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00016879 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | R04E5.2 encodes a predicted transmembrane protein orthologous to humanACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2,C52D10.12, M02F4.3, and R13G10.4; by orthology with MAM3, R04E5.2 mayparticipate in metal homoeostasis; R04E5.2, MAM3, and ACDP1-ACDP4 belongto a family of proteins (sharing an ACD domain) from bacteria, yeast,plants, and metazoa; murine Acdp1 is a plasma membrane protein;bacterial proteins containing the ACD domain include CorC fromSalmonella typhimurium, which is involved in magnesium and cobaltefflux; R04E5.2 has no obvious function in RNAi assays. | Paper_evidence | WBPaper00004651 | |||||
WBPaper00005654 | |||||||||
WBPaper00013242 | |||||||||
WBPaper00013325 | |||||||||
WBPaper00013365 | |||||||||
WBPaper00013531 | |||||||||
WBPaper00028771 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 09 Nov 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable transmembrane transporter activity. Involved in determination of adult lifespan and positive regulation of gonad development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Jalili syndrome and renal hypomagnesemia 6. Is an ortholog of several human genes including CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1); CNNM3 (cyclin and CBS domain divalent metal cation transport mediator 3); and CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0060884 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:103) | ||||
EFO:MONDO:0014631 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:103) | ||||||
DOID:0111404 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:105) | ||||||
Molecular_info | Corresponding_CDS | R04E5.2 | |||||||
Corresponding_CDS_history | R04E5.2:wp272 | ||||||||
Corresponding_transcript | R04E5.2.1 | ||||||||
Other_sequence | MIC02161_1 | ||||||||
EL784675.1 | |||||||||
EL784329.1 | |||||||||
MI04241 | |||||||||
MI01658 | |||||||||
Associated_feature | WBsf648382 | ||||||||
WBsf1006254 | |||||||||
WBsf1006255 | |||||||||
WBsf1023471 | |||||||||
WBsf1023472 | |||||||||
WBsf1023473 | |||||||||
WBsf236090 | |||||||||
Experimental_info | RNAi_result | WBRNAi00002417 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00051245 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00017407 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00017409 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1014513 | ||||||||
Expr1038618 | |||||||||
Expr1154947 | |||||||||
Expr2010278 | |||||||||
Expr2028520 | |||||||||
Drives_construct | WBCnstr00025532 | ||||||||
Construct_product | WBCnstr00025532 | ||||||||
Microarray_results | SMD_R04E5.1 | ||||||||
SMD_R04E5.2 | |||||||||
179762_at | |||||||||
179763_s_at | |||||||||
A_12_P113829 | |||||||||
Aff_R04E5.1 | |||||||||
Aff_R04E5.2 | |||||||||
GPL13394_WBGene00019869 | |||||||||
GPL13914_R04E5.2 | |||||||||
GPL14144_R04E5.2_1548-1607_0.907_19_B | |||||||||
GPL14144_R04E5.2_1834-1893_0.897_20_C | |||||||||
GPL14144_R04E5.2_1932-1991_0.908_18_A | |||||||||
GPL19516_CGZ0030827 | |||||||||
GPL21109_R04E5.2 | |||||||||
GPL3518_CE28746 | |||||||||
GPL8304_CE_WBGene00019869_A | |||||||||
GPL8673_R04E5_2P01320 | |||||||||
GPL8673_R04E5_2P02184 | |||||||||
GPL8673_R04E5_2P02202 | |||||||||
GPL9450_R04E5.2 | |||||||||
cea2.p.151319 | |||||||||
Expression_cluster (131) | |||||||||
Interaction (3) | |||||||||
Map_info | Map | X | Position | 0.410087 | |||||
Positive | Positive_clone | R04E5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00050045 | ||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |