WormBase Tree Display for Gene: WBGene00007984
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WBGene00007984 | SMap | S_parent | Sequence | CHROMOSOME_I | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | irx | ||||||
Allele (42) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (14) | |||||||
Contained_in_operon | CEOP1895 | ||||||
Ortholog (62) | |||||||
Structured_description | Concise_description | irx-1 encodes a homeodomain-containing protein that is most similar to members of the Iroquois subclass of TALE (three amino acid loop extension) superclass atypical homeodomain proteins; IRX-1 functions downstream of the UNC-55 nuclear receptor in a transcriptional regulatory network that controls remodeling of the GABAergic DD neuron synapses during larval development. | Paper_evidence | WBPaper00002937 | |||
WBPaper00004402 | |||||||
WBPaper00024497 | |||||||
WBPaper00025054 | |||||||
WBPaper00040363 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 28 Oct 2011 00:00:00 | ||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in head muscle; hypodermis; intestine; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Is an ortholog of several human genes including IRX1 (iroquois homeobox 1); IRX3 (iroquois homeobox 3); and IRX5 (iroquois homeobox 5). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:1682 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14358) | ||
DOID:12930 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14361) | ||||
Molecular_info | Corresponding_CDS | C36F7.1 | |||||
Corresponding_CDS_history | C36F7.1:wp187 | ||||||
Corresponding_transcript | C36F7.1.1 | ||||||
Other_sequence | HBC22230_1 | ||||||
Dviv_isotig23212 | |||||||
Oden_isotig21744 | |||||||
JI167499.1 | |||||||
MHC03189_1 | |||||||
TX00146 | |||||||
Hbac_isotig02767 | |||||||
ES739950.1 | |||||||
MH06638 | |||||||
Associated_feature | WBsf649483 | ||||||
WBsf978267 | |||||||
WBsf984727 | |||||||
WBsf984728 | |||||||
WBsf984729 | |||||||
WBsf984730 | |||||||
WBsf1010391 | |||||||
WBsf1010392 | |||||||
WBsf1010393 | |||||||
Transcription_factor | WBTranscriptionFactor000355 | ||||||
Experimental_info | RNAi_result (18) | ||||||
Expr_pattern | Expr7467 | ||||||
Expr9678 | |||||||
Expr10339 | |||||||
Expr15623 | |||||||
Expr1025765 | |||||||
Expr1033472 | |||||||
Expr1146080 | |||||||
Expr2012868 | |||||||
Expr2031102 | |||||||
Drives_construct | WBCnstr00009282 | ||||||
WBCnstr00012611 | |||||||
WBCnstr00015265 | |||||||
Construct_product | WBCnstr00009282 | ||||||
WBCnstr00009289 | |||||||
WBCnstr00009290 | |||||||
WBCnstr00016568 | |||||||
WBCnstr00021770 | |||||||
Microarray_results | SMD_C36F7.1 | ||||||
189594_at | |||||||
A_12_P118593 | |||||||
A_12_P160045 | |||||||
A_12_P160046 | |||||||
A_12_P160047 | |||||||
A_12_P160048 | |||||||
Aff_C36F7.1 | |||||||
GPL13394_WBGene00007984 | |||||||
GPL13914_C36F7.1 | |||||||
GPL14144_C36F7.1_299-358_0.856_37_C | |||||||
GPL14144_C36F7.1_509-568_0.910_12_B | |||||||
GPL14144_C36F7.1_768-827_0.922_9_A | |||||||
GPL19516_CGZ0007960 | |||||||
GPL21109_C36F7.1 | |||||||
GPL3518_CE17526 | |||||||
GPL8304_CE_WBGene00007984_A | |||||||
GPL8304_CE_WBGene00007984_C | |||||||
GPL8673_C36F7_1P00057 | |||||||
GPL8673_C36F7_1P00261 | |||||||
GPL8673_C36F7_1P00458 | |||||||
GPL9450_C36F7.1 | |||||||
GPL9450_C41G7.7 | |||||||
cea2.p.04000 | |||||||
cea2.p.04315 | |||||||
Expression_cluster (193) | |||||||
Interaction (34) | |||||||
Map_info | Map | I | Position | 3.80092 | Error | 0.000995 | |
Positive | Positive_clone | C36F7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 5375 | |||||
4148 | |||||||
Pseudo_map_position | |||||||
Reference (17) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |