WormBase Tree Display for Gene: WBGene00007362
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WBGene00007362 | SMap | S_parent | Sequence | CHROMOSOME_V | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | cyp | ||||||
Allele (34) | |||||||
Strain | WBStrain00032677 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Ortholog (157) | |||||||
Paralog (44) | |||||||
Structured_description | Concise_description | cyp-35C1 encodes one of over 80 C. elegans cytochrome P450s, NADPH-dependent monooxygenases that metabolize endogenous and exogenous compounds; RT-PCR experiments indicate that cyp-35C1 mRNA is upregulated in response to treatment with xenobiotics, such as PCBs (polychlorinated biphenyls) or PAHs (polycyclic aromatic hydrocarbons); loss of cyp-35A/C gene family activity in the presence of xenobiotics can diminish the reproductive decline seen in wild-type worms treated with the same compounds. | Paper_evidence | WBPaper00025207 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 26 Feb 2009 00:00:00 | ||||||
Automated_description | Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2E1 (cytochrome P450 family 2 subfamily E member 1); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (30) | ||||||
Molecular_info | Corresponding_CDS | C06B3.3 | |||||
Corresponding_CDS_history | C06B3.3:wp51 | ||||||
Corresponding_transcript | C06B3.3.1 | ||||||
Other_sequence (12) | |||||||
Associated_feature | WBsf653350 | ||||||
WBsf234875 | |||||||
Experimental_info | RNAi_result | WBRNAi00078473 | Inferred_automatically | RNAi_primary | |||
WBRNAi00079025 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00028551 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00039849 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00010275 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00078479 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00079024 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00079023 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00092689 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr11593 | ||||||
Expr1025565 | |||||||
Expr1033170 | |||||||
Expr1143931 | |||||||
Expr2010740 | |||||||
Expr2028976 | |||||||
Drives_construct | WBCnstr00019074 | ||||||
WBCnstr00033800 | |||||||
Construct_product | WBCnstr00033800 | ||||||
Microarray_results | SMD_C06B3.3 | ||||||
189282_at | |||||||
189283_s_at | |||||||
A_12_P118637 | |||||||
Aff_C06B3.3 | |||||||
GPL13394_WBGene00007362 | |||||||
GPL13914_C06B3.3 | |||||||
GPL14144_C06B3.3_1131-1190_0.917_7_B | |||||||
GPL14144_C06B3.3_1441-1500_0.940_3_A | |||||||
GPL14144_C06B3.3_907-966_0.907_10_C | |||||||
GPL19516_CGZ0002797 | |||||||
GPL21109_C06B3.3 | |||||||
GPL3518_CE27662 | |||||||
GPL8304_CE_WBGene00007362_A | |||||||
GPL8673_C06B3_3P00202 | |||||||
GPL8673_C06B3_3P01132 | |||||||
GPL8673_C06B3_3P01412 | |||||||
GPL9450_C06B3.3 | |||||||
cea2.p.107923 | |||||||
Expression_cluster (311) | |||||||
Interaction (27) | |||||||
Map_info | Map | V | Position | 5.73606 | Error | 0.003174 | |
Positive | Positive_clone | C06B3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (12) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |