WormBase Tree Display for Gene: WBGene00003784
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WBGene00003784 | SMap | S_parent | Sequence | ZK1127 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | nos | ||||||
Allele (22) | |||||||
Legacy_information | [Seydoux G] No mutants known. Encodes protein with similarity to Drosophila nanos. Predicted gene ZK1127.1 | ||||||
Strain | WBStrain00022251 | ||||||
WBStrain00003947 | |||||||
WBStrain00022439 | |||||||
WBStrain00022445 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Ortholog (19) | |||||||
Paralog | WBGene00003783 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00020167 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
Structured_description | Concise_description | nos-2 encodes one of three genes in C. elegans that contains a putative zinc-binding domain similar to the one found in Drosophila nanos; nos-2 affects incorporation of primordial germ cells into the somatic gonad, is required redundantly with nos-1 to prevent primordial germ cells from dividing in starved animals and to maintain germ cell viability during larval development in hermaphrodites and in males, and also functions together with nos-1 and nos-3 in the hermaphrodite switch from spermatogenesis to oogenesis; nos-2 is expressed in the primordial germ cells around the time of gastrulation from a maternal RNA associated with P granules, and it is expressed coordinately with nos-1in a dynamic fashion until the embryonic 200-cell stage. | Paper_evidence | WBPaper00003692 | |||
WBPaper00003762 | |||||||
WBPaper00004672 | |||||||
Curator_confirmed | WBPerson48 | ||||||
Date_last_updated | 11 Mar 2005 00:00:00 | ||||||
Automated_description | Predicted to enable mRNA binding activity and zinc ion binding activity. Involved in oogenesis and regulation of cell cycle. Located in cytoplasm. Expressed in P0; P4; Z2; and Z3. Human ortholog(s) of this gene implicated in spermatogenic failure 12. Is an ortholog of human NANOS1 (nanos C2HC-type zinc finger 1); NANOS2 (nanos C2HC-type zinc finger 2); and NANOS3 (nanos C2HC-type zinc finger 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0070171 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:23044) | ||
Molecular_info | Corresponding_CDS | ZK1127.1 | |||||
Corresponding_transcript | ZK1127.1.1 | ||||||
Other_sequence | CJC04685_1 | ||||||
CJC06275_1 | |||||||
CSC01626_1 | |||||||
CBC00647_1 | |||||||
FD515793.1 | |||||||
CR01356 | |||||||
CRC01394_1 | |||||||
Associated_feature (14) | |||||||
Experimental_info | RNAi_result (41) | ||||||
Expr_pattern | Expr1159 | ||||||
Expr1161 | |||||||
Expr1031770 | |||||||
Expr1162550 | |||||||
Expr2014357 | |||||||
Expr2032598 | |||||||
Drives_construct | WBCnstr00035869 | ||||||
Construct_product | WBCnstr00035869 | ||||||
Antibody | WBAntibody00000247 | ||||||
Microarray_results | SMD_ZK1127.1 | ||||||
184943_s_at | |||||||
188236_s_at | |||||||
A_12_P116234 | |||||||
A_12_P140032 | |||||||
A_12_P142315 | |||||||
Aff_ZK1127.1 | |||||||
GPL14144_T02G5.11_292-351_0.945_1_A | |||||||
GPL19516_CGZ0032839 | |||||||
GPL19516_CGZ0032840 | |||||||
GPL19516_CGZ0056252 | |||||||
GPL19516_CGZ0056253 | |||||||
GPL21109_T02G5.11a | |||||||
GPL21109_T02G5.11b | |||||||
GPL21109_ZK1127.1.1 | |||||||
GPL3518_CE05121 | |||||||
GPL8304_CE_WBGene00003784_A | |||||||
GPL8304_CE_WBGene00003784_B | |||||||
GPL8304_CE_WBGene00003784_C | |||||||
GPL8304_CE_WBGene00020167_C | |||||||
GPL8673_T02G5_11P00280 | |||||||
GPL8673_T02G5_11P00367 | |||||||
GPL8673_ZK1127_1P00043 | |||||||
GPL8673_ZK1127_1P00132 | |||||||
GPL8673_ZK1127_1P00219 | |||||||
GPL9450_T02G5.11 | |||||||
GPL9450_ZK1127.1 | |||||||
cea2.d.36530 | |||||||
cea2.p.53987 | |||||||
Expression_cluster (190) | |||||||
Interaction (234) | |||||||
Map_info | Map | II | Position | 0.381622 | Error | 0.021659 | |
Positive | Positive_clone | ZK1127 | Author_evidence | Seydoux GC | |||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
Mapping_data | Multi_point | 4542 | |||||
Pseudo_map_position | |||||||
Reference (64) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |